NCT04374734

Brief Summary

Acute respiratory failure (ARF) is a common condition and a common reason for urgent medical consultation. Assessing the extent of respiratory impairment is important to improve the management of patients with ARF. When Acute respiratory failure is caused by pathology of the pulmonary parenchyma, quantification of pulmonary radiographic involvement may be a component of the initial assessment of severity. This radiographic quantification would only be usable in clinical routine if it can be automated and provide a real-time result. The objective of this work is to assess the feasibility of an automated technique for quantifying radiological lung damage in situations of known or potential ARF.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 5, 2020

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

April 28, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 5, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2020

Completed
Last Updated

October 7, 2021

Status Verified

April 1, 2020

Enrollment Period

3 months

First QC Date

April 28, 2020

Last Update Submit

October 6, 2021

Conditions

SARS (Severe Acute Respiratory Syndrome)

Keywords

SARSSevere Acute Respiratory SyndromeAutomated quantificationLung volumeThorax imaging

Outcome Measures

Primary Outcomes (1)

  • Retrospective study of the relationship between severe forms of ARF and the extent of lung involvement

    2 months

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients presenting a situation at risk of acute respiratory failure

You may qualify if:

  • Patients over 18 years of age
  • Presenting a situation at risk of acute respiratory failure
  • Requiring thorax imaging when they were treated.

You may not qualify if:

  • Patients with anatomically incomplete thoracic imaging (e.g., technical acquisition error).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Service d' Anesthésie Réanimation Chirurgicale

Strasbourg, 67091, France

Location

MeSH Terms

Conditions

Severe Acute Respiratory Syndrome

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsVirus DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2020

First Posted

May 5, 2020

Study Start

April 5, 2020

Primary Completion

June 30, 2020

Study Completion

June 30, 2020

Last Updated

October 7, 2021

Record last verified: 2020-04

Locations

FR(1)