Trends in Live Birth Rates Attributable to Assisted Reproductive Technology in British Columbia

NCT04373239 | Completed

• 1 other identifier: H20-00461-B
• Study Type: observational
• Target: 1,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

Investigators will examine trends in ART use in BC specifically. The use of ART has drastically changed the management of infertility, with worldwide estimates exceeding 1.8 million ART cycles in 2010 alone. Moreover, an excess of six million children have been conceived using ART. Although various countries have published their live birth rates associated with common ART treatment strategies, British Columbia has yet report on its rates. With varying differences in ART practices, whether clinical or laboratory, it is expected live birth rates due to ART to vary depending on region analyzed. Analyzing the live birth rate in BC would not only allow for a benchmark for assessing future improvement, and trends in infertility diagnosis and management, but also allow for comparison to other provinces and countries. The aim of this part of the study is to describe ART cycle contribution to live birth rate in BC from April 2008 to March 2018, which has not been addressed in the literature as of yet. Not only will it give healthcare providers and patients information about this emerging approach to infertility but also provide a impetus for healthy policy makers to adopt a model for partially or fully publicly funded ART, as seen in Ontario and soon Quebec.

Conditions

Assisted Reproductive Techniques

Outcome Measures

Primary Outcomes (1)

• Live birth rate

  Live birth rate

  Date of delivery

Study Arms (2)

Women in BC conceiving by ART

All women in BC registered in the Perinatal Services BC database having undergone Assisted Reproductive Technology. Assisted Reproductive Technology will consist of in vitro fertilization (+/-ICSI). Data from April 1, 2008 to March 31 2018 will be analyzed for live birth rate.

Procedure: Assisted Reproductive Technology

Women in BC conceiving spontaneously

he comparison group will be all women in BC registered in the Perinatal Services BC database with spontaneously conceived pregnancies between April 1, 2008 to March 31 2018.

Interventions

Assisted Reproductive Technology PROCEDURE

Assisted reproductive technology includes IVF and IVF+ICSI.

Women in BC conceiving by ART

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All women registered in Perinatal Services BC database with live births between April 2008 and March 2018.

You may qualify if:

• Nulliparous women registered in Perinatal Services BC database with live birth between April 2008 and March 2018

You may not qualify if:

• multiparous women
• women with missing data in Perinatal Services BC database including gravid, parity, age, date of birth

Sponsors & Collaborators

• University of British Columbia: lead

MeSH Terms

Interventions

Reproductive Techniques, Assisted

Intervention Hierarchy (Ancestors)

Reproductive Techniques; Therapeutics; Investigative Techniques

Study Officials

• Mohamed Bedaiwy, MD, PhD

  University of British Columbia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 9 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: April 29, 2020
• First Posted: May 4, 2020
• Study Start: April 1, 2008
• Primary Completion: March 1, 2018
• Study Completion: March 1, 2018
• Last Updated: December 13, 2024

Record last verified: 2020-04

Data Sharing

• IPD Sharing: Will not share