Evaluation of the Fluid Response of SARS-CoV-2 (COVID-19) Patients in Intensive Care; Pleth Variability Index

NCT04373213 | Unknown FDA Device

• 1 other identifier: EBYU COVİD PVI
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

In this study; We aimed to investigate the role of pleth variability index, which is a noninvasive method, in showing fluid response in SARS-CoV-2 (COVID-19) patients, which we know is appropriate fluid management.

Conditions

Pleth Variability Index

Outcome Measures

Primary Outcomes (1)

• Pleth variability index

  Pleth variability index levels

  1 month

Study Arms (2)

Pleth variability index

Patients undergoing fluid management with Pleth variability index

Diagnostic Test: Pleth variability index

hemodynamic

Patients undergoing fluid management with hemodynamic findings

Diagnostic Test: Pleth variability index

Interventions

Pleth variability index DIAGNOSTIC_TEST

The usefulness of Pleth variability index in predicting fluid response in patients with COVID 19

Pleth variability index; hemodynamic

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients over 18 years of age who have been hospitalized in the COVID 19 anesthesia intensive care unit

You may qualify if:

• Patients hospitalized in COVID 19 anesthesia intensive care unit
• Patients over the age of 18

You may not qualify if:

• Patients under the age of 18

Sponsors & Collaborators

• Erzincan University: lead

Study Sites (1)

Erzincan University

Erzincan, 24100, Turkey (Türkiye)

Location

Related Publications (5)

• Basso F, Berdin G, Virzi GM, Mason G, Piccinni P, Day S, Cruz DN, Wjewodzka M, Giuliani A, Brendolan A, Ronco C. Fluid management in the intensive care unit: bioelectrical impedance vector analysis as a tool to assess hydration status and optimal fluid balance in critically ill patients. Blood Purif. 2013;36(3-4):192-9. doi: 10.1159/000356366. Epub 2013 Dec 20.

  PMID: 24496190 BACKGROUND

• Claure-Del Granado R, Mehta RL. Fluid overload in the ICU: evaluation and management. BMC Nephrol. 2016 Aug 2;17(1):109. doi: 10.1186/s12882-016-0323-6.

  PMID: 27484681 BACKGROUND

• de Oliveira OH, Freitas FG, Ladeira RT, Fischer CH, Bafi AT, Azevedo LC, Machado FR. Comparison between respiratory changes in the inferior vena cava diameter and pulse pressure variation to predict fluid responsiveness in postoperative patients. J Crit Care. 2016 Aug;34:46-9. doi: 10.1016/j.jcrc.2016.03.017. Epub 2016 Mar 30.

  PMID: 27288609 RESULT

• Piskin O, Oz II. Accuracy of pleth variability index compared with inferior vena cava diameter to predict fluid responsiveness in mechanically ventilated patients. Medicine (Baltimore). 2017 Nov;96(47):e8889. doi: 10.1097/MD.0000000000008889.

  PMID: 29382017 RESULT

• Liu T, Xu C, Wang M, Niu Z, Qi D. Reliability of pleth variability index in predicting preload responsiveness of mechanically ventilated patients under various conditions: a systematic review and meta-analysis. BMC Anesthesiol. 2019 May 8;19(1):67. doi: 10.1186/s12871-019-0744-4.

  PMID: 31068139 RESULT

Study Officials

• ILKE KUPELI

  Dr.

  PRINCIPAL INVESTIGATOR

Central Study Contacts

ILKE KUPELI

CONTACT

05555485632; ilkeser2004@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assoc. prof.

Study Record Dates

• First Submitted: April 30, 2020
• First Posted: May 4, 2020
• Study Start: May 5, 2020
• Primary Completion: June 5, 2020
• Study Completion: June 15, 2020
• Last Updated: May 4, 2020

Record last verified: 2020-04

Locations

TU (1)