NCT04371861

Brief Summary

This study is designed to collect data on the complication rates and procedural success of using a transradial access approach to treat peripheral lesions in the lower extremities of a real world population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2020

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 1, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

June 29, 2020

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 28, 2021

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2022

Completed
Last Updated

July 10, 2023

Status Verified

June 1, 2021

Enrollment Period

1.2 years

First QC Date

April 29, 2020

Last Update Submit

July 6, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Radial access site complications

    Rates of occurrence in complications associated with transradial access.

    Procedure

  • Procedural Success

    Successful completion of intended procedure without access complications and without conversion to femoral access.

    Procedure

Study Arms (1)

Treatment of lower extremity lesion via transradial access.

Interventions performed are standard of care for treatment of a peripheral lesion.

Device: Peripheral Artery Treatment

Interventions

Peripheral lesions may be treated by any standard of care methods of treatment.

Treatment of lower extremity lesion via transradial access.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects planned to undergo treatment of a lower extremity lesion via transradial artery access.

You may qualify if:

  • Rutherford Category 2-5
  • Subject scheduled for a transradial intervention to treat a lesion in the lower extremities.
  • Willing to sign consent and agree to follow-up requirements.

You may not qualify if:

  • Previous failed transradial access attempt
  • Presence of or planned dialysis fistula.
  • Planned amputation
  • Previous or planned transradial access intervention +/- 30 days
  • Radial artery diameter \<2.5mm
  • No palpable radial artery
  • Established vasospastic disease
  • Known allergy to contrast that cannot be managed
  • Pregnant or lactating
  • Mentally incompetent or a prisoner
  • Currently participating in a clinical study that has not completed it's primary endpoint

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

UCSD

La Jolla, California, 92037, United States

Location

Northside Hospital

St. Petersburg, Florida, 33709, United States

Location

Cardiovascular Institute of the South

Lafayette, Louisiana, 70503, United States

Location

Mercy Hospital

Springfield, Missouri, 65804, United States

Location

Columbia University Medical Center

New York, New York, 10032, United States

Location

Sorin Medical, Inc.

New York, New York, 10065, United States

Location

University Hospitals

Cleveland, Ohio, 44106, United States

Location

Ascension Seton Hays Hospital

Kyle, Texas, 78640, United States

Location

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular Diseases

Study Officials

  • Mehdi Shishehbor, DO

    University Hospitals, Cleveland, OH

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 29, 2020

First Posted

May 1, 2020

Study Start

June 29, 2020

Primary Completion

August 28, 2021

Study Completion

June 30, 2022

Last Updated

July 10, 2023

Record last verified: 2021-06

Locations