NCT04370106

Brief Summary

Background and rationale: Venous leg ulcers (VLU) are slow healing wounds with a recurrence rate up to 70% and a 60% risk of becoming chronic. Currently the Swiss health care system does not take in consideration social and educational needs and support for VLU patients who transition from acute care (hospital care, outpatient care) to home based self-care. To fill this gap, this study proposes to create the Social Legs Program (SLP). Overall objectives: The objectives of the proposed study are to evaluate the impact of a frequented SLP for patients with VLU in terms of their therapeutic adherence and wound healing outcomes (wound size and wound recurrence). Methodology of the planned study: A randomized controlled trial with 268 participants in three Swiss French institutions is proposed. Expected results and impact: The findings of this study will generate new knowledge about support and care management of persons with VLU who transition between acute care settings and home care settings. The findings will contribute to the evidence base of clinical practice guidelines for the care of patients with VLU.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
268

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2023

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 30, 2020

Completed
3.6 years until next milestone

Study Start

First participant enrolled

December 1, 2023

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2025

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2025

Completed
Last Updated

January 27, 2023

Status Verified

January 1, 2023

Enrollment Period

1.3 years

First QC Date

April 28, 2020

Last Update Submit

January 26, 2023

Conditions

Keywords

leg clubeducationrecurrence

Outcome Measures

Primary Outcomes (3)

  • Adherence to therapy

    Adherence to therapy, including physical activity, leg elevation, ankle exercises, wearing compression stockings, will be measured in minutes

    six months

  • Wound healing

    Measurement of the impact of a social leg program on the relative reduction (in percent) of wound size in patients with VLU. Wound size will be measured using WoundWorks® imaging device

    six months

  • Wound recurrence

    Measurement of the impact of a social leg program on absolute number of participants experiencing a recurrence (in percent) within six months over number of participants who had a healed VLU.

    six months

Secondary Outcomes (6)

  • Wound Assessment

    six months

  • Self care

    six months

  • Depression

    six months

  • Multidimensional complexity

    six months

  • General nutritional status

    six months

  • +1 more secondary outcomes

Study Arms (2)

Control

NO INTERVENTION

Usual care for participants with existing VLU in the CG is defined as visiting the outpatient wound clinic/visits by the community care nurse as prescribed by the physician. Wound healing measurement, therapeutic adherence measurement, wound recurrence measurement, and questionnaires will be provided by the institute's nurses.

Social leg Program

OTHER

Usual care as described for the CG will also be provided to the IG. Wound healing measurement, therapeutic adherence measurement, wound recurrence measurement, and questionnaires will be provided by the institute's nurses. After baseline data collection (T0) and random allocation to the intervention group, this usual care will be enhanced by frequenting a social leg program.

Other: Social leg program

Interventions

Usual care as described for the CG will also be provided to the IG. Wound healing measurement, therapeutic adherence measurement, wound recurrence measurement, and questionnaires will be provided by the institute's nurses. After baseline data collection (T0) and random allocation to the intervention group, this usual care will be enhanced by frequenting a social leg program.

Social leg Program

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older,
  • with an existing diagnosed open VLU,
  • an ulcer surface \<2 cm2 or having a healed VLU,
  • proficiency in the French language

You may not qualify if:

  • \- Valid informed consent is not or cannot be given

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

IMAD

Carouge, Canton of Geneva, 1227, Switzerland

Location

Cité Génération Maison de santé

Onex, Canton of Geneva, 1213, Switzerland

Location

MeSH Terms

Conditions

Varicose UlcerRecurrence

Condition Hierarchy (Ancestors)

Varicose VeinsVascular DiseasesCardiovascular DiseasesLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Sebastian E Probst, Prof Dr

    HES-SO University of Applied Sciences and Arts Western Switzerland

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sebastian E Probst, Prof Dr

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2020

First Posted

April 30, 2020

Study Start

December 1, 2023

Primary Completion

March 30, 2025

Study Completion

August 31, 2025

Last Updated

January 27, 2023

Record last verified: 2023-01

Data Sharing

IPD Sharing
Will not share

Locations