NCT04366895

Brief Summary

A randomized clinical trial (RCT) was designed. The participants were randomly allocated into either of the two groups intervention or control group each of 14 participants. Participants in control group (Group-A) received conventional manufactured implant overdenture while participants in intervention group (Group-B) received CAD-CAM manufactured implant overdenture.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 21, 2020

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 29, 2020

Completed
9 months until next milestone

Study Start

First participant enrolled

January 20, 2021

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 20, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 21, 2022

Completed
Last Updated

November 9, 2022

Status Verified

November 1, 2022

Enrollment Period

1.4 years

First QC Date

April 21, 2020

Last Update Submit

November 6, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Implant survival

    The implants were considered surviving if they were clinically stable, functioning without any mobility

    1 year

Secondary Outcomes (2)

  • Survival rate of overdentures

    1 year

  • maximum biting force (MBF)

    1 year

Study Arms (2)

control

EXPERIMENTAL

Participants in control group (Group-A) received conventional manufactured implant overdenture

Other: conventional single implant overdenture

intervention

EXPERIMENTAL

participants in intervention group (Group-B) received CAD-CAM manufactured implant overdenture.

Other: 3d printed single implant overdenture

Interventions

conventional manufactured implant overdenture

control

CAD-CAM manufactured implant overdenture.

intervention

Eligibility Criteria

Age35 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • the participant should be completely edentulous ranging in age from 35 to 75 years
  • Angle's class I skeletal relationship
  • normal facial symmetry
  • adequate inter-arch space not less than 12mm
  • should be a cooperative patient -

You may not qualify if:

  • temporomandibular disorders
  • uncontrolled diabetes
  • bleeding disorders or anticoagulant therapy
  • flabby tissues or sharp mandibular residual ridge
  • neuromuscular disorders
  • Angle's class II and III skeletal relationship.
  • Patients who were heavy smokers
  • chemotherapy or radiotherapy or with severe psychiatric disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Msa Uni

Giza, 12451, Egypt

Location

MeSH Terms

Conditions

Mouth, Edentulous

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic DiseasesTooth Diseases

Study Officials

  • Dina Elawady, PHD

    Lecturer

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of Prosthodontics (principal investigator)

Study Record Dates

First Submitted

April 21, 2020

First Posted

April 29, 2020

Study Start

January 20, 2021

Primary Completion

June 20, 2022

Study Completion

August 21, 2022

Last Updated

November 9, 2022

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will not share

Locations