The Relationship Between Umbilical Cord ph and Feto-maternal Doppler Studies in Scheduled Nonlaboring Term Singleton Caesarean Deliveries

NCT04364308 | Suspended

• 1 other identifier: 358
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Perinatal asphyxia is a crucial reason for neonatal and childhood morbidity and death. Fetal and neonatal acidemia can be utilised as predictors for establishing such risk. Several researches have reported a marked relation between low values of fetal pH with short- and long-term adverse neonatal outcomes. Umbilical cord blood gas studies (UCGS) are considered critical data that gives an objective and certified evaluation of the oxygenation and metabolic status of the fetus. Before birth, the physician can evaluate fetal wellness through cardiotocography and prenatal ultrasound. Other studies had examined the role of fetal Doppler indices before birth and proposed that fetuses with lower impedance in the middle cerebral artery (MCA) or low cerebroplacental ratio (CPR) are at increased risk of adverse pregnancy outcome. However, no research has ever evaluated the possibility of a correlation between ultrasonographic fetal evaluation and fetal umbilical cord pH as a predictor of pre-delivery fetal pH. The goal of our study was to discovered a potential association between the venous umbilical ph cord blood at delivery and the ultrasonographic feto-maternal doppler indices in patients with a scheduled nonlaboring term singleton caesarean deliveries (SCD), this research is a novel finding.

Conditions

Fetal Hypoxia; Fetal Conditions

Keywords

Fetal Doppler; Ultrasound exam; cesarean delivery; umbilical cord ph; scheduled cesarean delivery; cerebroplacental ratio

Outcome Measures

Primary Outcomes (1)

• The venous umbilical cord pH at birth was correlated with ultrasound doppler parameters

  the investigators recordered venous umbilical cord pH and all fetal doppler parameters

  pre-intervention

Interventions

Fetal Echography OTHER

Fetal ultrasound and its parameters

Eligibility Criteria

• Age: 18 Years - 44 Years
• Gender Eligibility Details: the investigators enrolled only pregnant women
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

the investigators enrolled only low-risk pregnant women

You may qualify if:

• singleton term (37 0/7 - 41 6/7 weeks of gestation) pregnancies delivered by a scheduled nonlaboring term singleton caesarean deliveries

You may not qualify if:

• Pregnancies complicated by fetal malformations, stillbirth, preterm deliveries.

Sponsors & Collaborators

• University of Campania Luigi Vanvitelli: lead

Study Sites (1)

Università degli studi della Campania "Luigi Vanvitelli"- OB & Gyn -

Napoli, Italia, 80138, Italy

Location

MeSH Terms

Conditions

Fetal Hypoxia

Condition Hierarchy (Ancestors)

Fetal Diseases; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hypoxia; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, research , gynecology and obstetrics, Principal Investigator

Study Record Dates

• First Submitted: April 19, 2020
• First Posted: April 28, 2020
• Study Start: April 1, 2019
• Primary Completion: April 19, 2020
• Study Completion: September 1, 2024
• Last Updated: November 29, 2023

Record last verified: 2023-11

Locations

IT (1)