NCT04363918

Brief Summary

Erectile dysfunction (ED), as defined by the International Consultation on Sexual Medicine, is the consistent and recurrent inability to acquire or sustain an erection of sufficient rigidity and duration to engage in satisfactory sexual intercourse. In the search for other approaches to treat ED the use of bioelectrical stimulation (BES) has been successfully introduced and applied in clinical studies. In the search for other approaches to treat ED the use of bioelectrical stimulation (BES) has been successfully introduced and applied in clinical studies.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2019

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2019

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2019

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

April 21, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 27, 2020

Completed
Last Updated

April 27, 2020

Status Verified

April 1, 2020

Enrollment Period

3 months

First QC Date

April 21, 2020

Last Update Submit

April 24, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Erectile function

    Erectile Function With International Index of Erectile Function-5 Questionnaire: The IIEF-5 questionnaire score determined the presence and severity of ED: absent (\> 21), mild (17-21), mild / moderate (12-16), moderate (8-11) and severe (\<8)

    8 weeks

Study Arms (3)

intervention (IG1)

ACTIVE COMPARATOR
Device: bioelectric stimulation

intervention (MyoStim group)

ACTIVE COMPARATOR
Device: bioelectric stimulation

control (CG)

SHAM COMPARATOR
Device: bioelectric stimulation

Interventions

bioelectric stimulation

control (CG)intervention (IG1)intervention (MyoStim group)

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • men with known ED (defined as a score of less than 22 on the IIEF-5)
  • who had been in a stable relationship for more than 6 months
  • not taking any ED medication.

You may not qualify if:

  • neurogenic ED (due to spinal cord injury, Parkinson's disease, multiple sclerosis, prostatectomy)
  • hypogonadism (total testosterone \< 300 ng/ dl)
  • decompensated diabetes mellitus (fasting blood glucose \> 200 mg/dl and/or glycated hemoglobin \> 8%)
  • decompensated systemic arterial hypertension (SBP \> 160 and/or DBP \> 100)
  • morbid obesity
  • diagnosis of coronary heart disease and/or cerebrovascular disease
  • inability to understand the study objectives/technique or to provide informed consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mundo do Assoalho Pélvico

Porto Alegre, Rio Grande do Sul, 90540040, Brazil

Location

MeSH Terms

Conditions

Erectile Dysfunction

Condition Hierarchy (Ancestors)

Genital Diseases, MaleGenital DiseasesUrogenital DiseasesSexual Dysfunction, PhysiologicalMale Urogenital DiseasesSexual Dysfunctions, PsychologicalMental Disorders

Study Officials

  • Alexandre Fornari, PhD

    Federal University of Health Science of Porto Alegre

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 21, 2020

First Posted

April 27, 2020

Study Start

March 1, 2019

Primary Completion

June 1, 2019

Study Completion

November 1, 2019

Last Updated

April 27, 2020

Record last verified: 2020-04

Data Sharing

IPD Sharing
Will not share

Locations