Myocardial Involvement of Severe Acute Respiratory Syndrome-Cov-2 (Covid19) Infected Patients
COCARDE
Imaging Cardiac Phenotype of SARS-Cov-2 (Covid19) Infected Patients
2 other identifiers
observational
122
1 country
1
Brief Summary
The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown. Epidemiological studies report biological myocardial involvement in 10 to 25% of cases. The objective of this study is to cardiac phenotype using comprehensive cardiac imaging tools of patients infected with Covid 19 in order to explore the functional impact of the infection on the myocardium.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 4, 2020
CompletedFirst Submitted
Initial submission to the registry
April 9, 2020
CompletedFirst Posted
Study publicly available on registry
April 24, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 2, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
April 2, 2021
CompletedJune 1, 2021
May 1, 2021
12 months
April 9, 2020
May 28, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Left ventricular function
Left ventricular function evaluated by global longitudinal strain
Day 0
Left ventricular function
Left ventricular function evaluated by global longitudinal strain
Day 3
Left ventricular function
Left ventricular function evaluated by global longitudinal strain
Day 7
Secondary Outcomes (1)
inflammatory biological parameters
Day 0
Study Arms (1)
COVID + patients
Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR
Interventions
Electrocardiogram with measure of the Global Longitudinal Strain to evaluate myocardiac dysfunction
Eligibility Criteria
Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR
You may qualify if:
- Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR
You may not qualify if:
- Underage patients. Patients refusing to participate in research. Patients with a history of heart disease.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
UHToulouse
Toulouse, 31059, France
Related Publications (1)
Lairez O, Blanchard V, Balardy L, Vardon-Bounes F, Cazalbou S, Ruiz S, Collot S, Houard V, Rolland Y, Conil JM, Minville V. COCARDE Study-Cardiac Imaging Phenotype in Patients With COVID-19: Protocol for a Prospective Observational Study. JMIR Res Protoc. 2022 Jan 6;11(1):e24931. doi: 10.2196/24931.
PMID: 34751159DERIVED
Biospecimen
Inflammatory cytokines
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Vincent MINVILLE, PU-PH
University Hospital, Toulouse
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 9, 2020
First Posted
April 24, 2020
Study Start
April 4, 2020
Primary Completion
April 2, 2021
Study Completion
April 2, 2021
Last Updated
June 1, 2021
Record last verified: 2021-05