Familial and Environmental Factors Behind Migraine
1 other identifier
observational
80
0 countries
N/A
Brief Summary
Migraine is a chronic neurological disease characterized by recurrent moderate to severe headaches often in association with a number of autonomic nervous system symptoms. Migraines are believed to be due to a mixture of environmental and genetic factors. About two-thirds of cases run in families. Changing hormone levels may also play a role, as migraines affect slightly more boys than girls before puberty, but about two to three times more women than men after puberty. The risk of migraines usually decreases during pregnancy. The exact mechanisms of migraine are not known. It is, however, believed to be a neurovascular disorder. The primary theory is related to increased excitability of the cerebral cortex and abnormal control of pain neurons in the trigeminal nucleus of the brainstem.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2020
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2020
CompletedFirst Submitted
Initial submission to the registry
April 18, 2020
CompletedFirst Posted
Study publicly available on registry
April 22, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2020
CompletedApril 22, 2020
April 1, 2020
4 months
April 18, 2020
April 18, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Diagnosis of risk factors for migraine
Familial History
6 months
Study Arms (2)
Migraine patients
Control
Interventions
Thorough History of Patients and families
Eligibility Criteria
Patients suffering from Headache between 15 and 45 years old
You may qualify if:
- Fullfilled Migraine chriteria
You may not qualify if:
- Genereal Neurologic Disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- FAMILY BASED
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Ass. Prof.
Study Record Dates
First Submitted
April 18, 2020
First Posted
April 22, 2020
Study Start
April 1, 2020
Primary Completion
August 1, 2020
Study Completion
August 1, 2020
Last Updated
April 22, 2020
Record last verified: 2020-04