NCT04355013

Brief Summary

Observational study to compare core temperatures obtained by 6 methods in patients undergoing cardiac surgery under cardiopulmonary bypass.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 28, 2016

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 22, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 22, 2017

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

April 17, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 21, 2020

Completed
4.5 years until next milestone

Results Posted

Study results publicly available

October 17, 2024

Completed
Last Updated

May 7, 2025

Status Verified

April 1, 2025

Enrollment Period

1.2 years

First QC Date

April 17, 2020

Results QC Date

June 10, 2022

Last Update Submit

April 29, 2025

Conditions

Keywords

Core temperatureCardiac surgery

Outcome Measures

Primary Outcomes (1)

  • Agreement Between Different Core Temperature Methods

    Agreement between core temperatures obtained in arterial CPB output versus venous inlet of CPB, bladder, pulmonary artery, nasopharynx and forehead (Tcore). The measurements were compared between the different methods using the Bland-Altman method of repeated measures and expressed as mean difference (reference method-alternative method) plus CI95%.

    24 temperature measures per patient recorded at 5-min intervals for each method and averaged using the Bland-Altman method for repeated measures

Interventions

Monitoring core temperatures with probes placed in the arterial outlet and venous inlet of extracorporeal pump, pulmonary artery, bladder, nasopharinx and forehead using a doublé-sensor probe

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing cardiac surgery under cardiovascular bypass

You may qualify if:

  • Only patients requiring a pulmonary artery catheter were included.

You may not qualify if:

  • Sepsis or previous fever.
  • Previous bladder catheter without termistor
  • Deep hypothermic circulatory arrest.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IBSAL

Salamanca, 37007, Spain

Location

Related Publications (1)

  • Sastre JA, Lopez T, Moreno-Rodriguez MA, Reta-Ajo L, Rubia-Martin MC, Diez-Castro R. Reliability of different body temperature measurement sites during normothermic cardiac surgery. Perfusion. 2023 Apr;38(3):580-590. doi: 10.1177/02676591211069918. Epub 2022 Feb 8.

MeSH Terms

Conditions

Body Temperature Changes

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Dr. José A. Sastre
Organization
University Hospital of Salamanca

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

April 17, 2020

First Posted

April 21, 2020

Study Start

September 28, 2016

Primary Completion

November 22, 2017

Study Completion

November 22, 2017

Last Updated

May 7, 2025

Results First Posted

October 17, 2024

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

Locations