Asymptomatic COVID-19 Infection Among Healthcare Workers
Asymptomatic SARS- CoV2 Infection Among Healthcare Workers in Three University Hospitals: A Cross Sectional Study.
1 other identifier
observational
500
1 country
1
Brief Summary
To assess the seroprevalence of SARS-CoV-2 IgG in Health care workers in three University Hospitals
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 16, 2020
CompletedFirst Posted
Study publicly available on registry
April 21, 2020
CompletedStudy Start
First participant enrolled
May 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 10, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 10, 2020
CompletedJune 17, 2020
June 1, 2020
1 month
April 16, 2020
June 16, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Number of IGg seropositive health care workers
health care workers who have positive IGg in seum
single measurement from each person collected over 2 months
Secondary Outcomes (1)
Differentiation between low risk and high risk HCWs
2 months through out duration of study
Interventions
Blood samples will be collected from the enrolled HCWs. Sample collection, processing, and laboratory testing will follow guidance from the World Health Organization
Eligibility Criteria
Participants will be the HCWs at great risk of getting an infection which include those who are in direct contact with respiratory secretions.
You may qualify if:
- Age: From 25 to 60 years old
- Department: physicians and nurses from the operating room, critical care department, emergency department, pulmonology department.
You may not qualify if:
- pregnant
- Age over 60 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Cairo University Hospital
Cairo, 11559, Egypt
Related Publications (2)
Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M, Yu T, Wang Y, Pan S, Zou X, Yuan S, Shang Y. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020 May;8(5):475-481. doi: 10.1016/S2213-2600(20)30079-5. Epub 2020 Feb 24.
PMID: 32105632BACKGROUNDMizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill. 2020 Mar;25(10):2000180. doi: 10.2807/1560-7917.ES.2020.25.10.2000180.
PMID: 32183930BACKGROUND
Biospecimen
serum SARsCOV-2 IGg to assess immunological state of HCWs
Study Officials
- PRINCIPAL INVESTIGATOR
Ahmed M Mukhtar, M.D
Cairo University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- professor of anesthesia and intensive care
Study Record Dates
First Submitted
April 16, 2020
First Posted
April 21, 2020
Study Start
May 1, 2020
Primary Completion
June 10, 2020
Study Completion
June 10, 2020
Last Updated
June 17, 2020
Record last verified: 2020-06
Data Sharing
- IPD Sharing
- Will not share