Effects of a Multi-Ingredient Pre-Workout Supplement on Energy Expenditure During Running

NCT04352998 | Completed

• 1 other identifier: NorthernIU
• Study Type: interventional
• Target: 12
• Locations: 0 countries
• Sites: N/A

Brief Summary

The primary purpose of this study was to examine the acute effects of one versus two doses of a multi-ingredient pre-workout supplement on energy expenditure during moderate-intensity treadmill running. In addition, our second aim was to investigate the responses of associated metabolic factors (i.e. substrate utilization, measures of gas exchange), perceived exertion, and resting cardiovascular variables with one and two doses of the pre-workout supplement.

Conditions

Healthy

Keywords

caffeine; substrate utilization; thermogenic; fat oxidation

Outcome Measures

Primary Outcomes (1)

• Energy expenditure

  energy expenditure measured as kcals per minute

  30 minutes of exercise

Secondary Outcomes (4)

• substrate utilization

  30 minutes of exercise

• measures of gas exchange

  30 minutes of exercise

• perceived exertion

  30 minutes of exercise

• resting cardiovascular variables

  baseline and 30 minutes post-ingestion

Study Arms (3)

One dose pre-workout supplement condition

ACTIVE COMPARATOR

One dose/serving of a multi-ingredient pre-workout supplement was administered to the subjects.

Dietary Supplement: One dose pre-workout condition

Two dose pre-workout supplement condition

ACTIVE COMPARATOR

Two doses/servings of a multi-ingredient pre-workout supplement was administered to the subjects.

Dietary Supplement: Two dose pre-workout condition

Placebo condition

PLACEBO COMPARATOR

One dose/serving of a placebo was administered to the subjects.

Dietary Supplement: Placebo condition

Interventions

One dose pre-workout condition DIETARY_SUPPLEMENT

one dose of a multi-ingredient pre-workout supplement

One dose pre-workout supplement condition

Two dose pre-workout condition DIETARY_SUPPLEMENT

two doses of a multi-ingredient pre-workout supplement

Two dose pre-workout supplement condition

Placebo condition DIETARY_SUPPLEMENT

one dose of a placebo

Placebo condition

Eligibility Criteria

• Age: 19 Years - 29 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• ran ≥ 16 km per week

You may not qualify if:

• (i) history of medical or surgical events, including cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders; (ii) use of any medication; (iii) use of nutritional supplements; (iv) habitual use of caffeine (≥ one cup of coffee or caffeinated beverage per day); or (v) participation in another clinical trial or investigation of another investigational product within 30 days prior to screening/enrollment.

Sponsors & Collaborators

• Northern Illinois University: lead
• University of Wisconsin, La Crosse: collaborator
• Mayo Clinic: collaborator
• Nova Southeastern University: collaborator

Study Officials

• Clayton Camic, PHD

  Northern Illinois University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: April 16, 2020
• First Posted: April 20, 2020
• Study Start: May 16, 2016
• Primary Completion: May 16, 2016
• Study Completion: May 16, 2016
• Last Updated: April 20, 2020

Record last verified: 2020-04

Data Sharing

• IPD Sharing: Will not share