NCT04352010

Brief Summary

Psychotherapy interventions can roughly be grouped into compensation-oriented strategies (compensating for and and modifying personal deficits of patients) versus capitalization-oriented strategies (building on patients' personal strengths). Improvement of emotion regulation (compensation-oriented) as well as the activation of resilience (capitalisation-oriented) have been identified as important transdiagnostic factors in the treatment of mental disorders. The study aims to compare compensation vs. capitalization strategies by using two online programs, centered either on emotion-regulation ("REMOTION") or on activating resilience ("Res-Up!"). Res-Up! and REMOTION are administered as stand-alone intervention or as add-on treatment to standard psychotherapy. Participants will be randomly assigned to three study conditions (Res-Up!, REMOTION, waiting control group). Outcomes are assessed at baseline, after six weeks and after twelve weeks.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 25, 2020

Completed
19 days until next milestone

Study Start

First participant enrolled

April 13, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 17, 2020

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2022

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2023

Completed
Last Updated

July 6, 2022

Status Verified

July 1, 2022

Enrollment Period

2.2 years

First QC Date

March 25, 2020

Last Update Submit

July 4, 2022

Conditions

Keywords

Internet-based TherapyResilienceEmotion RegulationOutcome ResearchStrengthsPsychotherapy

Outcome Measures

Primary Outcomes (1)

  • Change on Brief Symptom Inventory - short form (BSI-18) over multiple time points

    Franke, 2000; Internationally used self-report of symptom severity of patients \[18 items\] that includes three symptom scales, each including six items: Somatization, Depression, and Anxiety. Each measured on a 5-point scale according to how much one has been bothered by the symptom in the prior week.

    Change from Baseline, then after six weeks and after twelve weeks

Secondary Outcomes (9)

  • Change on Patient Health Questionnaire-9 (PHQ-9) over multiple time points

    Baseline, then after six weeks and after twelve weeks

  • Change on Witten Resource Questionnaire (WIRF) over multiple time points

    Change from Baseline, then after six weeks and after twelve weeks

  • Change on Rosenberg-Self-Esteem Scale (RSES) over multiple time points

    Change from Baseline, then after six weeks and after twelve weeks

  • Change on Connor-Davidson Resilience Scale (CD-RISC-10) over multiple time points

    Change from Baseline, then after six weeks and after twelve weeks

  • Change on Self-assessment of Emotion Regulation Skills (Selbsteinschätzung emotionaler Kompetenzen; SEK-27) over multiple time points

    Change from Baseline, then after six weeks and after twelve weeks

  • +4 more secondary outcomes

Study Arms (3)

Online-Intervention "Res-Up!"

EXPERIMENTAL

Participants in the Res-Up! group get access to Res-Up! while waiting for psychotherapy or in addition to psychotherapy. Participants will answer questionnaires after inclusion as well as six and twelve weeks later.

Behavioral: Res-Up!

Online-Intervention "REMOTION"

EXPERIMENTAL

Participants in the REMOTION group get access to REMOTION while waiting for psychotherapy or in addition to psychotherapy. Participants will answer questionnaires after inclusion as well as six and twelve weeks later.

Behavioral: REMOTION

Wait-control group

EXPERIMENTAL

Participants in the wait-control group will not get access to the online-tools while waiting for psychotherapy or while in psychotherapy. Participants will answer questionnaires after inclusion, six weeks later and twelve weeks later.They get access to one of the online-tools after 12 weeks.

Other: Wait-Control Group

Interventions

Res-Up!BEHAVIORAL

Res-Up! is an internet-based intervention focusing on patients' strengths and positive experiences that have effects on distress, protective factors and quality of life. The intervention is based on the Personal Model of Resilience (PMR; Padesky and Mooney, 2012), which is a positive intervention that utilizes patients' strengths to overcome problems.The PMR activates resilient emotions, thoughts, metaphors, images and behaviors in four steps during five sessions about the aquisition of resilient strategies and their use in daily life. A variety of elements based on different psychotherapy approaches (Cognitive Behavioral Therapy, Emotion Focused Therapy, Positive Therapy etc.) are integrated in the program. Participants should work through one module per week. The intervention is conducted as I-CBT via the platform Minddistrict.Res-Up! is administered as a standalone or an add-on treatment to psychotherapy.

Online-Intervention "Res-Up!"
REMOTIONBEHAVIORAL

REMOTION is an internet-based intervention aimed at transdiagnostically reducing symptom severity and improving emotion regulation of psychotherapy patients. The structure of REMOTION is based on the idea of an extended process model of emotion regulation as postulated by J.J. Gross (2015). The program includes the following modules: introduction, psychoeducation, identification, selection, implementation and modification. A variety of elements based on different psychotherapy approaches (Cognitive Behavioral Therapy, Emotion Focused Therapy, Dialectical Behavior Therapy etc.) are integrated in the program. Participants should work through one module per week. REMOTION is administered as a standalone or an add-on treatment to psychotherapy.

Online-Intervention "REMOTION"

In the waiting control group participants will answer questionnaires and they will gain access to either REMOTION or Res-Up! after twelve weeks.

Wait-control group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of a mental disorder according to DSM-5
  • Recruited at the training centers of the German Association for Behavior Therapy (Deutsche Gesellschaft für Verhaltenstherapie, DGVT) at Muenster, Bielefeld and Dortmund or at the Center of Mental Health and Psychotherapy, Witten/Herdecke University (all outpatients clinics

You may not qualify if:

  • Insufficient German language skills
  • Current severe episode of major depression
  • Psychotic disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Witten/Herdecke University

Witten, North Rhine-Westphalia, 58455, Germany

RECRUITING

Related Publications (1)

  • Trimpop LF, Bielinski LL, Berger T, Willutzki U. Evaluation of Two Web-Based Interventions (Res-Up! and REMOTION) in Routine Outpatient Psychotherapy (Therapy Online Plus-TOP): Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2023 Mar 15;12:e41413. doi: 10.2196/41413.

MeSH Terms

Conditions

Mental DisordersEmotional Regulation

Condition Hierarchy (Ancestors)

Self-ControlSocial BehaviorBehavior

Study Officials

  • Ulrike Willutzki, Prof. Dr.

    Witten/Herdecke University

    STUDY CHAIR

Central Study Contacts

Leonie F Trimpop, M.Sc.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor, Clinical Psychology and Psychotherapy

Study Record Dates

First Submitted

March 25, 2020

First Posted

April 17, 2020

Study Start

April 13, 2020

Primary Completion

July 1, 2022

Study Completion

April 1, 2023

Last Updated

July 6, 2022

Record last verified: 2022-07

Locations