NCT04351815

Brief Summary

This study aimed to evaluated the interest of a short-term (2 weeks) prehabilitation program compared to no prehabilitation before thoracic or urological surgery

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Dec 2019

Typical duration for not_applicable

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 20, 2019

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 14, 2020

Completed
2 months until next milestone

First Posted

Study publicly available on registry

April 17, 2020

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 11, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 11, 2022

Completed
Last Updated

August 4, 2022

Status Verified

August 1, 2022

Enrollment Period

2.2 years

First QC Date

February 14, 2020

Last Update Submit

August 2, 2022

Conditions

Keywords

prehabilitation

Outcome Measures

Primary Outcomes (2)

  • Evaluated the change in physical condition of patient following a short prehabilitation compared to the initial assessment (6 minutes walk test)

    Change on the 6-minute walk test (distance covered over a time of 6 minutes in meters)

    7 months

  • Evaluated the change in physical condition of patient following a short prehabilitation compared to the initial assessment (Borg scale)

    Change in the Borg scale (exertion from 0 to 10: 0 meaning no exertion, 10 meaning maximal exertion)

    7 months

Secondary Outcomes (44)

  • Evaluated the change in cardio-respiratory capacity (VO2 max) of patient following a short prehabilitation at 15 days compared to the initial assessment

    15 days

  • Evaluated the change in cardio-respiratory capacity (spirometry: maximal voluntary ventilation) of patient following a short prehabilitation at 15 days compared to the initial assessment

    15 days

  • Evaluated the change in cardio-respiratory capacity (spirometry: vital capacity) of patient following a short prehabilitation at 15 days compared to the initial assessment

    15 days

  • Evaluated the change in cardio-respiratory capacity (spirometry: functional residual capacity) of patient following a short prehabilitation at 15 days compared to the initial assessment

    15 days

  • Evaluated the change in cardio-respiratory capacity (heart rate) of patient following a short prehabilitation at 15 days compared to the initial assessment

    15 days

  • +39 more secondary outcomes

Study Arms (2)

Short prehabilitation

EXPERIMENTAL

This arm will benefit from a 2 weeks prehabilitation program including a personalized dietetic and physical training program as well as psychological support.

Behavioral: Short term prehabilitation (2 weeks)

No prehabilitation

OTHER

This arm will not benefit from a prehabilitation program before surgery. Patients will be told to maintain a regular physical activity without support.

Other: No specific intervention

Interventions

* Initial assessment visit with a dietitian, a psychologist, a physiotherapist, a doctor (physical medicine) and a geriatrician (for patients over 75 years old) * Patient will be asked to follow a 2 weeks prehabilitation program * 2 months post-surgery assessment visit with a dietitian, a psychologist, a physiotherapist, a doctor (physical medicine) * 6 months post-surgery assessment visit with a dietitian, a psychologist, a physiotherapist, a doctor (physical medicine)

Short prehabilitation

* Standard care: Initial assessment visit with a dietitian, a psychologist, a physiotherapist, a doctor (physical medicine) and a geriatrician (for patients over 75 years old) * Patients will be asked to maintain regular physical activity without support * 2 months post-surgery assessment visit with a dietitian, a psychologist, a physiotherapist, a doctor (physical medicine) * 6 months post-surgery assessment visit with a dietitian, a psychologist, a physiotherapist, a doctor (physical medicine)

No prehabilitation

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men or women aged 55 or over
  • Having signed a consent form after a reflection period
  • Being affiliated to a Health Insurance plan.

You may not qualify if:

  • Pregnant, parturient or lactating women
  • Persons deprived of their liberty: minors or adults subject to legal protection measures or out of state to express their consent
  • Patients (men or women) aged \<55 years;
  • Inability to walk or initial physical assessment
  • Inability to complete questionnaires
  • Walk\> 450 meters in the 6 minute test
  • Patients under guardianship or curators.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Thoracic DiseasesUrologic Diseases

Condition Hierarchy (Ancestors)

Respiratory Tract DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Officials

  • Morgan Le Guen, MD

    Hopital Foch

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 14, 2020

First Posted

April 17, 2020

Study Start

December 20, 2019

Primary Completion

March 11, 2022

Study Completion

March 11, 2022

Last Updated

August 4, 2022

Record last verified: 2022-08