NCT04347473

Brief Summary

Patient with moderate-to-severe plaque psoriasis will receive Ilumya with or without Halog ointment.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for phase_4

Timeline
Completed

Started Apr 2020

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 6, 2020

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

April 13, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 15, 2020

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2021

Completed
Last Updated

April 15, 2020

Status Verified

April 1, 2020

Enrollment Period

9 months

First QC Date

April 13, 2020

Last Update Submit

April 13, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Body surface area

    evaluation of body surface area percentage affected by psoriasis where 1 palm is equivalent to 1%

    16 weeks

Study Arms (1)

Ilumya

EXPERIMENTAL

Ilumya 100mg subcutaneous at weeks 0, 4 and 16.

Drug: Ilumya Injectable Product

Interventions

IL-23 injection

Ilumya

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female adult ≥ 18 years of age;
  • Diagnosis of moderate-to-severe chronic plaque-type psoriasis as defined by
  • BSA 10%
  • PGA ≥3
  • PASI ≥12
  • Must be a candidate for phototherapy and/or systemic therapy
  • Females of childbearing potential (FCBP) must have a negative serum pregnancy test at Screening and negative urine pregnancy test at Baseline. FCBP who engage in activity in which conception is possible must use one of the approved contraceptive options: hormonal contraception; intrauterine device (IUD); tubal ligation; or partner's vasectomy; Male or female condom diaphragm with spermicide, cervical cap with spermicide, or contraceptive sponge with spermicide.

You may not qualify if:

  • Non-plaque forms of psoriasis
  • Women of childbearing potential who are pregnant, intend to become pregnant, or are lactating
  • Presence of significant uncontrolled medical condition that in the opinion of the investigator would affect patient safety during the trial.
  • Active or untreated latent tuberculosis (TB)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Psoriasis Treatment Center of Central New Jersey

East Windsor, New Jersey, 08520, United States

RECRUITING

MeSH Terms

Conditions

Psoriasis

Condition Hierarchy (Ancestors)

Skin Diseases, PapulosquamousSkin DiseasesSkin and Connective Tissue Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: open label
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 13, 2020

First Posted

April 15, 2020

Study Start

April 6, 2020

Primary Completion

December 30, 2020

Study Completion

March 1, 2021

Last Updated

April 15, 2020

Record last verified: 2020-04

Data Sharing

IPD Sharing
Will not share

Locations