NCT04342091

Brief Summary

To evaluate the efficacy microneedling via a professional tattoo machine in revitalizing hair follicles in patients with fibrosing alopecia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 6, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 10, 2020

Completed
12 months until next milestone

Study Start

First participant enrolled

April 9, 2021

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 8, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 8, 2022

Completed
1 year until next milestone

Results Posted

Study results publicly available

April 13, 2023

Completed
Last Updated

April 13, 2023

Status Verified

March 1, 2023

Enrollment Period

12 months

First QC Date

April 6, 2020

Results QC Date

March 21, 2023

Last Update Submit

March 21, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Total Area Hair Count (Frontal)

    Total number of hairs over an area of 1cm\^2

    6 months

  • Total Area Hair Count (Vertex)

    Total number of hairs over an area of 1 cm\^2

    6 months

Secondary Outcomes (8)

  • Hair Shaft Diameters (Frontal)

    6 months

  • Hair Shaft Diameters (Vertex)

    6 months

  • Number of Hair Follicles (Frontal)

    6 months

  • Number of Hair Follicles (Vertex)

    6 months

  • Vellus Hairs (Frontal)

    6 months

  • +3 more secondary outcomes

Study Arms (1)

Microneedling

EXPERIMENTAL

Participants with fibrosing alopecia will receive microneedling with a tattoo machine.

Device: SOL Nova Device

Interventions

A SOL Nova Device (brand) is tattoo machine will be used to stimulate hair regrowth.

Microneedling

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy Female
  • Diagnosing Fibrosing alopecia

You may not qualify if:

  • Any female with hair loss for other reasons
  • Males
  • Patients with cardiac conditions or renal insufficiency
  • Pregnant patients
  • Patients containing the following who would make poor candidates for microneedling, such as skin conditions, diabetes, history of keloid formation
  • Anything additional existing comorbidities that in the opinion of the investigator may cause unnecessary risk for the patient to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yale University

New Haven, Connecticut, 06519, United States

Location

Results Point of Contact

Title
Brett King
Organization
Yale University

Study Officials

  • Brett King, MD, PhD

    Associate Professor of Dermatology, Yale University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 6, 2020

First Posted

April 10, 2020

Study Start

April 9, 2021

Primary Completion

April 8, 2022

Study Completion

April 8, 2022

Last Updated

April 13, 2023

Results First Posted

April 13, 2023

Record last verified: 2023-03

Data Sharing

IPD Sharing
Will not share

Locations