Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury

NCT04341974 | Completed

• 1 other identifier: CEAVC 13881/2018
• Study Type: observational
• Target: 423
• Locations: 1 country
• Sites: 1

Brief Summary

The perioperative approach adopted in a cohort of adult oncological patients undergoing major abdominal surgery will be described. In particular, the physician's attitude toward use of sCr for identification of patients at risk for PO-AKI will be described, as well as the patients who should be reassessed in the long term for progression toward CKD. The incidence and risk factors associated with PO-AKI and renal function deterioration within a year postoperatively will be also evaluated.

Conditions

Surgery; Malignancy; Acute Kidney Injury; Cronich Kidney Disease

Keywords

serum creatinine; kidney dysfunction

Outcome Measures

Primary Outcomes (1)

• Adoption of serum creatinine as marker of acute kidney injury postoperively

  Number of actual patients screened postoperatively

  3rd postoperative day

Secondary Outcomes (3)

• Incidence of acute kidney injury

  3rd postoperative day

• Adoption of serum creatinine as marker of long term kidney dysfunction

  12 month after surgery

• Incidence of long term kidney dysfunction

  12 month after surgery

Study Arms (1)

surgical patients

Adult patients undergoing major elective general abdominal surgery for ontological disease

Diagnostic Test: Serum creatinine

Interventions

Serum creatinine DIAGNOSTIC_TEST

Will be described: 1) the number of patients actually screened with postoperative serum creatinine and 2) the number of patients actually screened with the same parameter at the long-term after surgery

surgical patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients were older than 18 years, underwent surgery under general anesthesia for oncological disease who underwent major elective general abdominal surgery from November 2016 to February 2017 at the Department of Anaesthesia of Careggi Hospital

You may qualify if:

• Adult patients
• Scheduled for elective surgery
• Surgery for oncological disease

You may not qualify if:

• Patients undergoing postoperative chemotherapy
• Patients who died within 12 month after surgery

Sponsors & Collaborators

• Careggi Hospital: lead

Study Sites (1)

Azienda Ospedaliero Universitaria Careggi

Florence, 50100, Italy

Location

Related Publications (1)

• Villa G, De Rosa S, Scire Calabrisotto C, Nerini A, Saitta T, Degl'Innocenti D, Paparella L, Bocciero V, Allinovi M, De Gaudio AR, Ostermann M, Romagnoli S. Perioperative use of serum creatinine and postoperative acute kidney injury: a single-centre, observational retrospective study to explore physicians' perception and practice. Perioper Med (Lond). 2021 May 25;10(1):13. doi: 10.1186/s13741-021-00184-6.

  PMID: 34030728 DERIVED

MeSH Terms

Conditions

Neoplasms; Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, clinical researcher

Study Record Dates

• First Submitted: April 8, 2020
• First Posted: April 10, 2020
• Study Start: January 1, 2019
• Primary Completion: January 1, 2020
• Study Completion: March 31, 2020
• Last Updated: April 14, 2020

Record last verified: 2020-04

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)