NCT04341051

Brief Summary

We conducted Single-center prospective observational study to evaluate the improvement of peripheral vascular perfusion monitored with near-infrared spectroscopy, in patients undergoing endovascular surgery after performing sciatic nervous block.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
31

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2020

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2020

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

April 8, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 10, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2020

Completed
Last Updated

April 10, 2020

Status Verified

April 1, 2020

Enrollment Period

2 months

First QC Date

April 8, 2020

Last Update Submit

April 8, 2020

Conditions

Keywords

regional oxigen saturation

Outcome Measures

Primary Outcomes (1)

  • Regional Oxigen saturation downstream of popliteal region

    NIRS misuration of delivered oxigen T0)before the execution of sciatic popliteal block T1) after 5 minuts, T2)15 minuts, T3)30 minuts, T4)after the revascularization

    1 day

Secondary Outcomes (2)

  • Comparing the results between AOCP IIa to III (Fontaine Classification)

    1 day

  • Comparing the results between patients with occlusion of a single arthery and patients with more occluded arthery

    1 day

Study Arms (1)

Case

we will observe the regional saturation of O2 through NIRS at the following time: T0(before peripheral anesthesia); T1 (5 minutes from the block); T2 (15 minutes from the block); T3 (30 minutes from the block); T4 (after revascularization); At each interval PA, SpO2 and NIRS were also recorded in the contralateral limb as control data.

Other: Case

Interventions

CaseOTHER

Mesure with NIRS regional saturation in patients undergoing popliteal block during vascular surgery for chronic obliterating arteriopathy (IIa to III Fontaine Classification)

Case

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients suffering from Peripheral Artery Occlusive Disease undergoing popliteal sciatic nerve block as analgesic procedure before revascularization surgery

You may qualify if:

  • age: \> 18 years
  • Peripheral artery occlusive desease involving popliteal, tibial and/or peroneal artery
  • Stadiation IIa to III in Fontaine classification
  • Eligibility for PTA or Stenting

You may not qualify if:

  • trophic alteration of the application site of the NIRS
  • less than 18 years
  • Pregnancy
  • need of sedation during the procedure
  • revascularization performed as emergency surgery
  • Allergic reactions with local anaesthetic
  • Previous surgery involving the interested artery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Peripheral Arterial Occlusive Disease 1

Study Officials

  • Fabio Gobbi, Doctor

    A.O.U. Città della Salute e della Scienza

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Fabio Gobbi, Doctor

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

April 8, 2020

First Posted

April 10, 2020

Study Start

April 1, 2020

Primary Completion

May 31, 2020

Study Completion

May 31, 2020

Last Updated

April 10, 2020

Record last verified: 2020-04