Treatment of Dentin Hypersensitivity Using Different Desensitizing Agents
The Effect of Using Two Desensitizing Agents Alone and In Combination on Dentin Permeability and Hypersensitivity
1 other identifier
interventional
30
1 country
1
Brief Summary
Treatment of Dentin Hypersensitivity Using Theobromine , Remin Pro , and Combination of Both Materials
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Aug 2019
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2019
CompletedFirst Submitted
Initial submission to the registry
March 2, 2020
CompletedFirst Posted
Study publicly available on registry
April 10, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2022
CompletedApril 10, 2020
April 1, 2020
2 years
March 2, 2020
April 9, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Visual analogue scale pain score
0 = no pain to 10=severe exagerated pain
1 month
Study Arms (3)
Theobromine
EXPERIMENTALNatural extract from Cocoa
Remin Pro
ACTIVE COMPARATORFluoride , Hydroxyapatite , and Xylitol
Combination
EXPERIMENTALRemin Pro and Theobromine
Interventions
Eligibility Criteria
You may qualify if:
- Patients that aged 18-50 years.
- Patients in good general health.
- Patients that have accessible teeth demonstrating signs of sensitivity.
You may not qualify if:
- Any chronic debilitating disease that could influence study outcomes.
- Partial dentures, orthodontic appliances, implants or restorations in a poor state of repair that could influence study outcomes.
- Intolerance or hypersensitivity to the study desensitizing agents or their ingredients.
- Desensitising treatment or tooth bleaching within 8 weeks of screening.
- Daily use of medications that might influence the perception of pain.(
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Al-Azhar University , Faculty of Dental medicine for Girls
Cairo, 11111, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
March 2, 2020
First Posted
April 10, 2020
Study Start
August 1, 2019
Primary Completion
August 1, 2021
Study Completion
April 1, 2022
Last Updated
April 10, 2020
Record last verified: 2020-04
Data Sharing
- IPD Sharing
- Will share