Outcome of Cataract Surgery With Uveitis
Outcome of Cataract Surgery in Patient With Uveitis
1 other identifier
interventional
50
0 countries
N/A
Brief Summary
Aim of the study is to evaluate outcome of cataract surgery in different types of uveitis as regarding best corrected visual acuity (BCVA) and rate of post operative complications.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Apr 2020
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 28, 2020
CompletedFirst Posted
Study publicly available on registry
April 3, 2020
CompletedStudy Start
First participant enrolled
April 10, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 20, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 20, 2022
CompletedApril 3, 2020
March 1, 2020
2.1 years
March 28, 2020
April 1, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (8)
final postoperative uncorrected visual acuity (UCVA)
post operative uncorrected visual acuity which mean visual acuity without spectacle correction
1 week post operative
final postoperative uncorrected visual acuity (UCVA)
post operative uncorrected visual acuity which mean visual acuity without spectacle correction
1month post operative
final postoperative uncorrected visual acuity (UCVA)
post operative uncorrected visual acuity which mean visual acuity without spectacle correction
3months post operative
final postoperative uncorrected visual acuity (UCVA)
post operative uncorrected visual acuity which mean visual acuity without spectacle correction
6months post operative
Final post operative best corrected visual acuity (BCVA)
Post operative visual acuity with spectacle correction
1 week post operative
Final post operative best corrected visual acuity (BCVA)
Post operative visual acuity with spectacle correction
1month post operative
Final post operative best corrected visual acuity (BCVA)
Post operative visual acuity with spectacle correction
3months post operative
Final post operative best corrected visual acuity (BCVA)
Post operative visual acuity with spectacle correction
6months post operative
Secondary Outcomes (2)
incidence of postoperative complications
6 months post operative
Reactivation of intraocular inflammation
6 months post operative
Study Arms (1)
Uncorrected and best corrected visual acuity
OTHERMeasuring of uncorrected and best corrected visual acuity after phaco emulsification and irrigation aspiration cataract surgery
Interventions
cataract surgery in form of phaco emulsification or irrigation aspiration
Eligibility Criteria
You may qualify if:
- \- Visually significant cataract ( means opacification of the crystalline lens adequate to interfere with vision)in patients with uveitis controlled for at least 1month.
You may not qualify if:
- Irreversible pathology affecting outcome e.g. macular scar ,optic atrophy, and retinal detachment.
- Patients with active uveitis (means inflammation inside the eye).
- Patients less than 16 years old.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (5)
Carpentier SJ, Jung JL, Patnaik JL, Pecen PE, Palestine AG. A Cross-Sectional Online Survey Identifies Subspecialty Differences in the Management of Pediatric Cataracts Associated with Uveitis. Ophthalmol Ther. 2020 Jun;9(2):293-303. doi: 10.1007/s40123-020-00245-x. Epub 2020 Mar 10.
PMID: 32157612BACKGROUNDChen JL, Bhat P, Lobo-Chan AM. Perioperative Management of Uveitic Cataracts. Adv Ophthalmol Optom. 2019 Aug;4:325-339. doi: 10.1016/j.yaoo.2019.04.014. Epub 2019 May 18.
PMID: 31788579BACKGROUNDYangzes S, Seth NG, Singh R, Gupta PC, Jinagal J, Pandav SS, Gupta V, Gupta A, Ram J. Long-term outcomes of cataract surgery in children with uveitis. Indian J Ophthalmol. 2019 Apr;67(4):490-495. doi: 10.4103/ijo.IJO_846_18.
PMID: 30900580BACKGROUNDJinagal J, Gupta G, Agarwal A, Aggarwal K, Akella M, Gupta V, Suri D, Gupta A, Singh S, Ram J. Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis. Indian J Ophthalmol. 2019 Jan;67(1):69-74. doi: 10.4103/ijo.IJO_713_18.
PMID: 30574896BACKGROUNDEl Gharbawy SA, Darwish EA, Abu Eleinen KG, Osman MH. Efficacy of addition of nepafenac 0.1% to steroid eye drops in prevention of post-phaco macular edema in high-risk eyes. Eur J Ophthalmol. 2019 Jul;29(4):453-457. doi: 10.1177/1120672118799626. Epub 2018 Sep 11.
PMID: 30203671BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Ashraf Khalaf Al Husseini, professor
Assiut University
- PRINCIPAL INVESTIGATOR
Wael Mohammed Ahmed Soliman, professor
Assiut University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant lecturer at Ophthalmology departmentAssiut University Faculty of Medicine
Study Record Dates
First Submitted
March 28, 2020
First Posted
April 3, 2020
Study Start
April 10, 2020
Primary Completion
May 20, 2022
Study Completion
December 20, 2022
Last Updated
April 3, 2020
Record last verified: 2020-03
Data Sharing
- IPD Sharing
- Will not share