Allergen Provocations- HCA Children's Hospital
Allergen Provocations at Hans Christian Andersen Children's Hospital
1 other identifier
observational
8,000
1 country
1
Brief Summary
A prospective study of all allergen provocations performed in children at the Hans Christian Andersen Children's Hospital.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2018
CompletedFirst Submitted
Initial submission to the registry
March 31, 2020
CompletedFirst Posted
Study publicly available on registry
April 2, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2038
ExpectedStudy Completion
Last participant's last visit for all outcomes
October 1, 2039
July 10, 2025
July 1, 2025
20 years
March 31, 2020
July 5, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
The association of allergy tests with the result of allergen provocation
The value of specific IgE and SPT to predict the outcome of a allergen provocation
5 years
Study Arms (15)
Antibiotics
Children aged 0-18 years investigated for allergy to antibiotics
Milk
Children aged 0-18 years investigated for allergy to milk
Egg
Children aged 0-18 years investigated for allergy to egg
Peanut
Children aged 0-18 years investigated for allergy to peanut
Hazelnut
Children aged 0-18 years investigated for allergy to hazelnut
Sesame
Children aged 0-18 years investigated for allergy to sesame
Wheat
Children aged 0-18 years investigated for allergy to wheat
walnut
Children aged 0-18 years investigated for allergy to walnut
cashew
Children aged 0-18 years investigated for allergy to cashew
Pistachio
Children aged 0-18 years investigated for allergy to pistachio
Almond
Children aged 0-18 years investigated for allergy to almond
Soy
Children aged 0-18 years investigated for allergy to soy
Fish
Children aged 0-18 years investigated for allergy to fish
Shellfish
Children aged 0-18 years investigated for allergy to shellfish
Poppy seed
Children aged 0-18 years investigated for allergy to poppy seed
Interventions
Titrated provocation with allergen
Eligibility Criteria
Children referred to the department of pediatrics for investigation of allergy to foods or antibiotics
You may qualify if:
- clinical suspicion of allergy to foods or antibiotics informed concent -
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Josefine Gradmanlead
Study Sites (1)
Hans Christian Andersen Children's Hospital
Odense, Odense C, 5000, Denmark
Related Publications (2)
Gradman J, Petersen BT, Halken S. Oral food challenge with raw egg: Sixty-minute- compared with 30-minute dosing interval. Clin Exp Allergy. 2022 Sep;52(9):1114-1117. doi: 10.1111/cea.14187. Epub 2022 Jul 4. No abstract available.
PMID: 35719001DERIVEDPetersen BT, Gradman J. Prospective study of 5-day challenge with penicillins in children. BMJ Paediatr Open. 2020 Aug 4;4(1):e000734. doi: 10.1136/bmjpo-2020-000734. eCollection 2020.
PMID: 32818157DERIVED
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 17 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Consultant, phd
Study Record Dates
First Submitted
March 31, 2020
First Posted
April 2, 2020
Study Start
October 1, 2018
Primary Completion (Estimated)
October 1, 2038
Study Completion (Estimated)
October 1, 2039
Last Updated
July 10, 2025
Record last verified: 2025-07
Data Sharing
- IPD Sharing
- Will not share