NCT04330937

Brief Summary

The clinical trial consists in checking the antioxidant effect of citrolive on low density cholesterol.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2017

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

October 16, 2019

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2020

Completed
2 months until next milestone

First Posted

Study publicly available on registry

April 2, 2020

Completed
Last Updated

April 2, 2020

Status Verified

March 1, 2020

Enrollment Period

2.2 years

First QC Date

October 16, 2019

Last Update Submit

March 30, 2020

Conditions

Outcome Measures

Primary Outcomes (2)

  • Blood pressure

    The systolic and diastolic blood pressure was measured with an OMRON oscilimétrilo sphygmomanometer

    The change in systolic and diastolic blood pressure is observed after three months of intake of the product under investigation

  • Biochemistry and blood count

    the hematological profile is analyzed with the Horiba ABX Oentra 80 analyzer. Biochemical profile with the ILAB 600 analyzer

    The change is observed after three months of intake of the product under investigation

Secondary Outcomes (7)

  • Weight

    The change is observed after three months of intake of the product under investigation

  • Height

    The change is observed after three months of intake of the product under investigation

  • BMI

    The change is observed after three months of intake of the product under investigation

  • Perimeters

    The change is observed after three months of intake of the product under investigation

  • Folds

    The change is observed after three months of intake of the product under investigation

  • +2 more secondary outcomes

Study Arms (2)

experimental group

EXPERIMENTAL

volunteers consume 1 capsule per day for 3 months. (500 mg citrolive).

Dietary Supplement: dietetics

control group Placebo (sucrose)

PLACEBO COMPARATOR

volunteers consume 1 capsule per day for 3 months. (saccharose).

Dietary Supplement: dietetics

Interventions

dieteticsDIETARY_SUPPLEMENT

90 days of consumption

control group Placebo (sucrose)experimental group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Not belonging to the group of individuals considered as priorities by the Third Joint Task Force for the prevention of cardiovascular diseases due to high risk.
  • Present total cholesterol figures greater than 200 milligrams / deciliter and / or low density cholesterol figures greater than 130 milligrams / deciliter so that after applying the cardiovascular risk table (SCORE) they present a current risk of less than 5% of suffer an ischemic event in a period of 10 years, being without pharmacological treatment.
  • Present several cardiovascular risk factors with cholesterolemia figures close to 200 milligrams / deciliters and / or low density cholesterol figures close to 130 milligrams / deciliters.

You may not qualify if:

  • \. chronic or terminal illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Catholic University of Murcia

Murcia, 30107, Spain

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

October 16, 2019

First Posted

April 2, 2020

Study Start

October 1, 2017

Primary Completion

November 30, 2019

Study Completion

February 1, 2020

Last Updated

April 2, 2020

Record last verified: 2020-03

Locations