NCT04330222|Unknown
Cambridge 7 Tesla Cerebral Small Vessel Disease Study
CamSVD
Imaging the Arterial Pathology in Cerebral Small Vessel Disease Using 7 Tesla Magnetic Resonance Imaging
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CamSVD
Imaging the Arterial Pathology in Cerebral Small Vessel Disease Using 7 Tesla Magnetic Resonance Imaging
Sponsor study identifier
observational
210
1 country
1
Study Start
March 9, 2020
Actual (reported)Primary Completion
January 12, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
January 12, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
CamSVD is jointly sponsored by the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. We aim to explore and understand the underlying arterial pathology in Cerebral Small Vessel Disease (SVD) using ultra-high-field 7 Tesla MRI. We will optimise 7T Time-of-Flight MR angiography, blood suppressed MR sequence and phase-contrast (PC) MR angiography for visualization of perforating lenticulostriate arteries. This optimised sequences will be used to determine the range of arterial pathologies seen in individuals presenting with lacunar strokes. The pathologies of the perforating lenticulostriate arteries will be correlated with conventional clinical risk factors, cognition and radiological markers of SVD.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 12, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 9, 2020
Actual (reported)March 30, 2020
Actual (reported)April 1, 2020
Actual (reported)January 12, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
January 12, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Range and pattern of pathology seen in the perforating arteries like presence or absence of focal atheroma and narrowing
March 2020-
Differences in morphology of perforating arteries between SVD patients and healthy volunteers
March 2020-
Correlation of morphology of perforating arteries with cardiovascular risk factors and radiological markers of SVD
March 2020-
Diagnostic Imaging
Cognitive Assessment
Lacunar Strokes due to Cerebral Small Vessel Disease
University of Cambridge
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
Hugh Markus, FMedSci
University of Cambridge Department of Clinical Neurosciences
First Submitted
March 30, 2020
First Posted
April 1, 2020
Study Start
March 9, 2020
Actual (reported)Primary Completion
January 12, 2024
Estimated (date passed)White Matter Hyperintensities Subtypes in Cerebral Small Vessel Disease : 7 Tesla Ultra-high Resolution Imaging MRI
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
January 12, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
September 21, 2022
Record last verified: 2022-09
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Source: ClinicalTrials.gov.
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