Pattern of Upper Gastrointestinal Lesions in Upper Egypt : Clinical, Endoscopic and Pathological Evaluation

NCT04328324 | Unknown

• 1 other identifier: 2832020
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Upper Gastrointestinal (UGI) symptoms are among the commonest complaints for which patients seek medical attention, with the annual prevalence of dyspepsia approximating 25% . Endoscopy holds an important place in the diagnosis of UGI conditions by enabling visualization, photography, ultrasonography, and biopsying of suspicious lesions . It gives a better diagnostic yield over radiology particularly in the investigation of upper gastrointestinal bleeding, inflammatory conditions of the upper gastro-intestinal track like esophagitis, gastritis and duodenitis as well as the diagnosis of Mallory Weiss tears and vascular malformations .Dyspepsia in the absence of any other symptom was the indication for UGIE in the vast majority of patients. Close to 80% of our patients presented with dyspepsia not associated with any other symptom and in 50% of the patients the endoscopic findings were normal \[4\]. Other common reasons for UGIE were GERD symptoms, recurrent vomiting, dyspepsia associated with weight loss and patients with symptoms of UGI bleeding . Gastritis was the most frequent endoscopic finding in our patients, followed by duodenitis .Gastric ulcer was diagnosed more frequently than duodenal ulcers . Taking a biopsy is very helpful in diagnosis in our study. H. pylori colonization of the gut is the main cause of chronic gastritis and the principal etiological agent of gastric cancer and peptic ulcer disease . Gastric cancer was diagnosed, by endoscopy, about eight times more frequently in patients presenting with an alarm symptom like recurrent vomiting, dyspepsia together with weight loss or UGI bleeding .

Conditions

Pattern of Upper Gastrointestinal Lesions

Outcome Measures

Primary Outcomes (1)

• Pattern of upper gastrointestinal lesions

  We will see what common GIT lesions happen in patients of upper Egypt

  1 year

Interventions

Endoscopy PROCEDURE

Diagnostic upper Git endoscopy

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patient undergoing elective and urgent upper GIT endoscopy either therapeutic or diagnostic. In elrajhi endoscopy unit

You may qualify if:

• \- All patient undergoing elective and urgent upper GIT endoscopy either therapeutic or diagnostic.

You may not qualify if:

• Patient undergoing endoscopic intervention for previously detected endoscopic lesion

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Interventions

Endoscopy

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Surgical; Diagnostic Techniques and Procedures; Diagnosis; Minimally Invasive Surgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: RHMHasanen

Study Record Dates

• First Submitted: March 28, 2020
• First Posted: March 31, 2020
• Study Start: March 30, 2020
• Primary Completion: May 1, 2020
• Study Completion: April 30, 2021
• Last Updated: March 31, 2020

Record last verified: 2020-03