NCT04320095

Brief Summary

The purpose of this study is to describe how Bizact Tonsillectomy Device might affect operative time and intraoperative blood loss in pediatric patients undergoing tonsillectomy, and compare these parameters to the standard technique in tonsillectomy at our institution, which is electrocautery.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2020

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 22, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 24, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

June 1, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2021

Completed
Last Updated

March 31, 2020

Status Verified

March 1, 2020

Enrollment Period

8 months

First QC Date

March 22, 2020

Last Update Submit

March 30, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Operative time

    The study will be considered success if the mean intra operative time using Bizact device is less than that using electrocautery

    during the procedure

Secondary Outcomes (1)

  • Intraoperative blood loss

    during the procedure

Study Arms (4)

Bizact device for one tonsil

EXPERIMENTAL

Bizact tonsillecotmy device which is an advanced bipolar device using radiofrequency and pressure to ligate the encountered vessels during tonsillectomy.

Device: Bizact tonsillectomy device

Electrocautery for second tonsil

ACTIVE COMPARATOR

Electrocautery is the standard technique used at our institution.

Device: Bizact tonsillectomy device

Bizact device for both tonsils

EXPERIMENTAL

Consecutive cases of tonsillectomy will be done using Bizact device and compare the operative time collectively for those cases and compare it to same number of cases done using the standard procedure ( Electrocautery)

Device: Bizact tonsillectomy device

Electrocautery for both tonsils

ACTIVE COMPARATOR

As explained on the above arm description

Device: Bizact tonsillectomy device

Interventions

Bizact tonsillectomy device is an advanced bipolar instrument that uses radiofrequency energy and pressure to ligate vessels interposed between its jaws. The energy produced by the device is automatically adjusted based on tissue impedance in an attempt to minimize thermal tissue damage.

Bizact device for both tonsilsBizact device for one tonsilElectrocautery for both tonsilsElectrocautery for second tonsil

Eligibility Criteria

Age2 Years - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Children scheduled for tonsillectomy at Alberta Children Hospital
  • Tonsillectomy for either recurrent tonsillitis or sleep-disordered breathing.

You may not qualify if:

  • Craniofacial abnormalities
  • Bleeding disorders
  • Complex medical background

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Khaloud Al Bahri, MD

CONTACT

Warren Yunker, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 22, 2020

First Posted

March 24, 2020

Study Start

June 1, 2020

Primary Completion

February 1, 2021

Study Completion

February 1, 2021

Last Updated

March 31, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share