Efficiency of Diode Laser Activated Irrigation on Healing of Periapical Tissues
1 other identifier
interventional
24
1 country
1
Brief Summary
Study is a Randomized clinical trial conducted at Endodontic department- Ain Shams university Cairo. Egypt. 24 eligible patients were selected and included in the study to compare healing ability of diode laser activated irrigation versus conventional root canal treatment using CBCT
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jul 2017
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2020
CompletedFirst Submitted
Initial submission to the registry
March 7, 2020
CompletedFirst Posted
Study publicly available on registry
March 17, 2020
CompletedMarch 18, 2020
March 1, 2020
2 years
March 7, 2020
March 16, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Assess post-operative healing using CBCT in a period of 12 month when Laser activated irrigation was used during root canal treatment
12 months
Study Arms (2)
Laser activated irrigation LAI
EXPERIMENTALDiode Laser activated irrigation
conventional root canal treatment
PLACEBO COMPARATORmock LAI , conventional root canal treatment 2.5% sodium hypochlorite
Interventions
Eligibility Criteria
You may qualify if:
- Adult patients age between 18-50 years
- Medically free patients.
- Patients suffering from acute or chronic infection with symptomatic apical periodontitis with Necrotic pulp
- Preoperative Pain
- Sensitivity to percussion
- Periapical radiographic X-ray showing periapical lesion with no gutta percha in canal
- Occlusal contact with opposing teeth
You may not qualify if:
- Pregnant females.
- Patients having a significant systemic disorder or history of drug abuse
- Patients who had administrated analgesics or antibiotics during the last 12 hours preoperatively.
- Patients having bruxism or clenching
- Teeth having:
- No occlusal contact
- No sensitivity to percussion
- Greater than grade I mobility.
- Pocket depth greater than 5mm.
- No possible restorability
- Procedural errors
- Previous Root canal treatment
- Open apex
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Endodontic department - Faculty of Dentistry Ainshams University
Cairo, Egypt
Related Publications (1)
Hamdy Ismail H, Obeid MF, ElSaid Hassanein E. The efficiency of single-session photobiomodulation on healing of periapical bone lesions using CBCT: a randomized clinical trial. Lasers Med Sci. 2025 Jan 23;40(1):31. doi: 10.1007/s10103-024-04242-5.
PMID: 39847087DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Maram Obeid, PhD
AinShams University
- STUDY CHAIR
Ehab Hassanien, PhD
Ainshams University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Masking Details
- Single blinded
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD candidate
Study Record Dates
First Submitted
March 7, 2020
First Posted
March 17, 2020
Study Start
July 1, 2017
Primary Completion
July 1, 2019
Study Completion
January 1, 2020
Last Updated
March 18, 2020
Record last verified: 2020-03
Data Sharing
- IPD Sharing
- Will not share