NCT04311164

Brief Summary

The present study is part of an overarching study being conducted in Denmark at Steno Diabetes Center Copenhagen (SDCC) and Nordsjællands Hospital Hillerød (NOH), Steno Tech, that aims to develop and ultimately, in a randomized controlled trial (RCT), test approaches that can assist people with type 1 diabetes in obtaining optimal outcomes using CSII. Through a large-scale, questionnaire-based online survey enriched with data from national registers, this sub-study contributes to this overarching aim by exploring the importance of individual differences across a wide range of factors, including demographic, socioeconomic, health status, psychosocial and preference structures, for optimal use of CSII in people with type 1 diabetes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
770

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2020

Shorter than P25 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 11, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 17, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

May 15, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2020

Completed
Last Updated

February 1, 2021

Status Verified

January 1, 2021

Enrollment Period

5 months

First QC Date

March 11, 2020

Last Update Submit

January 29, 2021

Conditions

Keywords

continous subcutaneous insulin infusionclinical outcomespsychological outcomeseducational aspectspreferencesinequality and inequity

Outcome Measures

Primary Outcomes (1)

  • Glycated Hemoglobin A1c (HbA1c)

    Information on HbA1c in mmol/mol will be extracted from national registers

    13 years (from 2008 (beginning of register) to present)

Secondary Outcomes (7)

  • Other diabetes-relevant biomarkers

    13 years (from 2008 (beginning of register) to present)

  • General diabetes and insulin pump-specific behavior

    1 day (measured at one time point only, i.e., at the survey completion date for each participant)

  • Psychological well-being

    1 day (measured at one time point only, i.e., at the survey completion date for each participant)

  • Diabetes distress

    1 day (measured at one time point only, i.e., at the survey completion date for each participant)

  • Hypoglycemia anxiety

    1 day (measured at one time point only, i.e., at the survey completion date for each participant)

  • +2 more secondary outcomes

Study Arms (2)

Steno Tech Survey Respondents

A cohort of individuals with type 1 diabetes treated with CSII at either SDCC or NOH participating in the Steno Tech Survey.

Other: Questionnaire-based survey

General Type 1 Diabetes Population

A cohort consisting of the entire population of people with type 1 diabetes in Denmark not included in the Steno Tech Survey cohort (ca. 25.000 individuals).

Other: No intervention given.

Interventions

The online questionnaire-based survey is composed of multiple items including pre-coded (multiple choice) questions, dichotomous (yes/no) questions, rating scales and validated questionnaire scales to measure general and diabetes/insulin pump-specific behavior, psychological concepts and preferences.

Steno Tech Survey Respondents

No intervention was given.

General Type 1 Diabetes Population

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population consists of two groups/cohorts: 1. Steno Tech Survey Respondents: A cohort of individuals with type 1 diabetes treated with CSII at either Steno Diabetes Center Copenhagen or Nordsjaellands Hospital Hilleroed participating in the Steno Tech Survey. 2. General Type 1 Diabetes Population: A cohort consisting of the entire population of people with type 1 diabetes in Denmark not included in the Steno Tech Survey cohort (ca. 25.000 individuals).

The Steno Tech Survey Repondents group: * Adult (18+ years) * Type 1 diabetes * Insulin pump user * Danish-speaking The General Type 1 Population group: * Adult (18+ years) * Type 1 diabetes

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (2)

Steno Diabetes Center Copenhagen

Gentofte Municipality, 2820, Denmark

Location

Nordsjællands Hospital Hillerød

Hillerød, 3400, Denmark

Location

Related Publications (2)

  • Lorenzen JT, Madsen KP, Cleal B, Joensen LE, Norgaard K, Pedersen-Bjergaard U, Schmidt S, Rytter K, Willaing I. Associations between use of diabetes technology and diabetes distress: a Danish cross-sectional survey of adults with type 1 diabetes. BMJ Open. 2024 Mar 25;14(3):e080053. doi: 10.1136/bmjopen-2023-080053.

  • Rytter K, Madsen KP, Andersen HU, Hommel E, Pedersen-Bjergaard U, Schmidt S, Norgaard K. Associations between insulin pump self-management and HbA1c in type 1 diabetes. Diabet Med. 2023 Jun;40(6):e15068. doi: 10.1111/dme.15068. Epub 2023 Feb 25.

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD, Researcher

Study Record Dates

First Submitted

March 11, 2020

First Posted

March 17, 2020

Study Start

May 15, 2020

Primary Completion

October 15, 2020

Study Completion

October 15, 2020

Last Updated

February 1, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations