Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders

NCT04308915 | Completed

• 1 other identifier: IITK/IEC/2017-18II/2
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with characteristic deficits in social functioning and presence of stereotypic behavior. Several research studies have examined potential deficits in cognitive skills, such as working memory, in this condition. A meta-analysis of the studies aimed at evaluating working memory (WM) in autistic population suggested deficits in visual and verbal aspects of WM. Working memory training has also been studied in other neurodevelopmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD). The study includes development of mobile-based games for training WM and other cognitive skills in patients and the evaluation of such training in reducing symptoms of ASD. These games may also be useful for other neurodevelopmental disorders.

Conditions

Autism Spectrum Disorder

Keywords

digital intervention; serious games

Outcome Measures

Primary Outcomes (2)

• Corsi Task Block Span

  It is an indicator of working memory. The value ranges between 0 and 9. Higher values mean better outcome.

  change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)

• Corsi Task Total Score

  It is an indicator of working memory. The minimum value is 0, the maximum value has no limit. Higher values mean better outcome.

  change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)

Secondary Outcomes (1)

• Autism Treatment Evaluation Checklist Total Score

  change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)

Study Arms (1)

Game-based training

EXPERIMENTAL

Participants play games for cognitive training

Behavioral: Game-based cognitive training

Interventions

Game-based cognitive training BEHAVIORAL

A suite of 5 games is presented to the participants for training working memory

Game-based training

Eligibility Criteria

• Age: 5 Years - 16 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Diagnosis of Autism Spectrum Disorder or another related neurodevelopmental disorder with symptoms of ASD

You may not qualify if:

• Inability to use smartphones/tablets
• Serious intellectual disabilities.
• Sensory impairment

Sponsors & Collaborators

• Indian Institute of Technology Kanpur: lead

Study Sites (1)

Indian Institute of Technology Kanpur

Kanpur, Uttar Pradesh, 208016, India

Location

Related Publications (1)

• de Vries M, Prins PJ, Schmand BA, Geurts HM. Working memory and cognitive flexibility-training for children with an autism spectrum disorder: a randomized controlled trial. J Child Psychol Psychiatry. 2015 May;56(5):566-76. doi: 10.1111/jcpp.12324. Epub 2014 Sep 26.

  PMID: 25256627 BACKGROUND

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 11, 2020
• First Posted: March 16, 2020
• Study Start: September 6, 2018
• Primary Completion: October 31, 2018
• Study Completion: October 31, 2018
• Last Updated: March 17, 2020

Record last verified: 2020-03

Data Sharing

• IPD Sharing: Will not share

Locations

IN (1)