Epidemiology of Cardiovascular Diseases and Their Risk Factors in Regions of Russian Federation

NCT04306822 | Completed

• 1 other identifier: 01201178178
• Study Type: observational
• Target: 22,906
• Locations: 0 countries
• Sites: N/A

Brief Summary

The study carried out in 2012-2014 years. The aim was to evaluate the prevalence of CVD and their RF in different regions of the Russian Federation and to develop epidemiological models of the CVD risk profile for the population based on traditional factors, as well as to assess the contribution of traditional and "new" cardiovascular risk factors to the mortality rate of the country's population based on domestic data. Thirteen regions were included. We examined 22,906 males and females, aged 25-64 years. The examination consist of anthropometry; the measurement of BP, resting heart rate, and a 12-lead standard electrocardiography (ECG) in a supine position. The personal interview information was collected using a structured questionnaire, and included socio-demographic and socio-economic measures; health parameters; medical history; stress, and depression. Continued monitoring of mortality, the latest mortality update includes deaths through 2019.

Conditions

Risk Factor, Cardiovascular; Non-communicable Diseases; Cardiovascular Diseases

Keywords

epidemiology; risk factor; adult; non-communicable diseases; cardio-vascular diseases; dietary habits; arterial hypertension; smoking; physical activity; hypercholesterinemia

Outcome Measures

Primary Outcomes (1)

• The number of fatal and non-fatal events

  cardiovascular death, noncardiovascular death, all-cause death, the triple composite of cardiovascular death, non-fatal MI or non-fatal stroke, fatal MI, fatal stroke, non-fatal MI, non-fatal stroke, hospitalization for HF, coronary angiography, PCI, and CABG

  6 years

Eligibility Criteria

• Age: 25 Years - 64 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

The study participants were randomly selected from 13 regions of Russian Federation between 2012-2014. The final sample included 22,906 individuals (8353 males, 13553 females) who completed an interview and medical tests (response rate 80%).

You may qualify if:

• randomly selected males and females aged 25-64 years from 13 regions of Russian Federation

You may not qualify if:

• males and females younger than 24 years and older than 64 years

Sponsors & Collaborators

• National Research Center for Preventive Medicine: lead
• National Medical Research Center for Cardiology, Ministry of Health of Russian Federation: collaborator
• Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health: collaborator

MeSH Terms

Conditions

Noncommunicable Diseases; Cardiovascular Diseases; Feeding Behavior; Hypertension; Smoking; Motor Activity

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior, Animal; Behavior; Vascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 10, 2020
• First Posted: March 13, 2020
• Study Start: January 1, 2012
• Primary Completion: January 1, 2014
• Study Completion: January 1, 2020
• Last Updated: March 17, 2020

Record last verified: 2020-03