Ewing Sarcoma Family of Tumors (ESFT): A 15-year Experience From a Tertiary Care Cancer Center in Upper Egypt

NCT04300179 | Completed

• 1 other identifier: ESFT_Upp_Egypt
• Study Type: observational
• Target: 59
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to identify demographic \& disease characteristics in pediatric oncology patients diagnosed with Ewing Sarcoma Family of Tumors (ESFT) \& treatment outcomes in these patients.

Conditions

Soft Tissue Neoplasms; Bone Neoplasms; Neoplasms

Keywords

Ewing's sarcoma (ES); Peripheral primitive neuroectodermal tumor (PNET)

Outcome Measures

Primary Outcomes (2)

• Overall survival (OS)

  Participants will be retrospectively followed forward in time from the date of initiation of treatment till death from any cause, an expected average of 5 years

  From date of treatment initiation until the date of death from any cause or patients censored at last follow up, whichever came first, assessed up to 60 months

• Event Free Survival (EFS)

  Participants will be retrospectively followed forward in time from the date of initiation of treatment till occurrence of an event from any cause (tumor progression, relapse) or death, an expected average of 5 years

  From date of treatment initiation until the date of event from any cause or patients censored at last follow up, whichever came first, assessed up to 60 months

Eligibility Criteria

• Age: Up to 19 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Pediatric cancer patients, those diagnosed with Ewing Sarcoma Family of Tumors (ESFT), in the period from 2000 January till 2015 December, and received treatment at the pediatric oncology department, their medical records will be retrospectively reviewed for data collection.

You may qualify if:

• Patients whose age less than 19 years. Patients diagnosed with Ewing Sarcoma Family of Tumors (ESFT).

You may not qualify if:

• Patients whose age more than 19 years. Patients diagnosed with other bone \& soft tissue neoplasms.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

South Egypt Cancer Institute

Asyut, Egypt

Location

MeSH Terms

Conditions

Soft Tissue Neoplasms; Bone Neoplasms; Neoplasms; Sarcoma, Ewing; Neuroectodermal Tumors, Primitive, Peripheral

Condition Hierarchy (Ancestors)

Neoplasms by Site; Bone Diseases; Musculoskeletal Diseases; Osteosarcoma; Neoplasms, Bone Tissue; Neoplasms, Connective Tissue; Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type; Sarcoma; Neuroectodermal Tumors, Primitive; Neoplasms, Neuroepithelial; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms, Glandular and Epithelial; Neoplasms, Nerve Tissue

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Pediatric Oncology

Study Record Dates

• First Submitted: March 5, 2020
• First Posted: March 9, 2020
• Study Start: July 7, 2020
• Primary Completion: December 16, 2020
• Study Completion: December 16, 2020
• Last Updated: December 17, 2020

Record last verified: 2020-12

Locations

EG (1)