NCT04299100

Brief Summary

This is a pilot, prospective, randomized controlled trial of a novel sleep health program versus no sleep intervention in chronic pain patients. The Sleep Health program will consist of weekly home-based videos and digital materials termed "Self-Management for Sleep Care", which will provide participants with information on how to improve their sleep through education on sleep hygiene, relaxation training, and cognitive behavioural components. Patients will be also be screened through undiagnosed sleep apnea. For those determined to have suspected undiagnosed moderate or severe sleep apnea, they will be receive a recommendation for referral to a sleep clinic as part of standard of care. The study aims to evaluate the feasibility and effectiveness of the Sleep Health Program which includes the videos and digital materials and screening for sleep apnea in patients with chronic pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2020

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 18, 2019

Completed
4 months until next milestone

First Posted

Study publicly available on registry

March 6, 2020

Completed
4 months until next milestone

Study Start

First participant enrolled

July 9, 2020

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 28, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 28, 2021

Completed
Last Updated

December 10, 2021

Status Verified

December 1, 2021

Enrollment Period

1.2 years

First QC Date

November 18, 2019

Last Update Submit

December 9, 2021

Conditions

Outcome Measures

Primary Outcomes (2)

  • Feasibility of Sleep Health Program

    Proportion of participants at baseline, and who completed the follow-up visits at 8 weeks.

    8 weeks

  • Feasibility of Sleep Health Program

    Proportion of participants at baseline, and who completed the follow-up visits at 6 months.

    6 months

Secondary Outcomes (2)

  • Efficacy of Sleep Health Program on Functional Outcomes of Sleep Questionnaire-10.

    6 months

  • Efficacy of Sleep Health Program on Insomnia Severity Index

    6 months

Study Arms (3)

Control Group

NO INTERVENTION

Participants randomized to the Control Group will receive usual care from their pain physician.

Sleep Health Program - Suspected No/mild sleep apnea

EXPERIMENTAL

Participants randomized to the Sleep Health Program with no/mild sleep apnea.

Behavioral: Sleep Health Program for Participants with No/Mild Sleep Apnea

Sleep Health Program - Suspected Moderate/severe sleep apnea

EXPERIMENTAL

Participants randomized to the Sleep Health Program with suspected moderate/severe sleep apnea.

Behavioral: Sleep Health Program for Participants with Moderate/Severe Sleep Apnea

Interventions

Participants randomized to the Sleep Health Program will receive the Self-Management for Sleep Care videos and digital materials.

Also known as: Sleep Health group
Sleep Health Program - Suspected No/mild sleep apnea

Participants randomized to the Sleep Health Program with suspected moderate/severe sleep apnea will receive the Self-Management for Sleep Care videos and digital materials, and be recommended for referral to a sleep clinic as part of standard of care.

Also known as: Sleep Health group
Sleep Health Program - Suspected Moderate/severe sleep apnea

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients (≥18 years old) with cognitive capability
  • Diagnosed with chronic non-cancer pain for \> 3 months
  • Reports sleep disturbances such as difficulty falling asleep, staying asleep, or problems waking up too early (responds "Mild", "Moderate", "Severe", or "Very Severe" to items 1, 2, or 3 on the Insomnia Severity Index).

You may not qualify if:

  • Patients with chronic pain secondary to a neoplasm or metastasis
  • Conditions potentially interfering with comprehension and delivery of informed consent, such as certain neurological or psychiatric disorders
  • Patients with severe insomnia (Insomnia Severity Index ≥ 22)
  • Restless legs syndrome
  • Periodic limb movement disorder
  • Sleep apnea
  • Narcolepsy
  • Seizure disorder
  • Patients who are pregnant
  • Currently undergoing a psychological treatment for insomnia
  • Participants who require an urgent sleep physician referral (within four weeks) due to serious medical conditions or safety critical-occupations according to the 2011 Canadian Thoracic Society (CTS) guidelines (e.g. unstable ischemic heart disease, recent cerebrovascular disease, congestive heart failure, refractory systemic hypertension, pulmonary hypertension, hypercapnia respiratory failure).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

St. Michael's Hospital

Toronto, Ontario, M5B 1W8, Canada

Location

Toronto Rehab Institute (TRI)

Toronto, Ontario, M5G 2A2, Canada

Location

Women's College hospital

Toronto, Ontario, M5S 1B2, Canada

Location

Toronto Western Hopsital, Pain Clinic, Dept. of Anesthesia

Toronto, Ontario, M5T2S8, Canada

Location

Mount Sinai Hospital, Department of Anesthesia

Toronto, Ontario, Canada

Location

MeSH Terms

Conditions

Sleep Apnea SyndromesChronic Pain

Condition Hierarchy (Ancestors)

ApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Frances Chung, MBBS FRCPC

    UHN/ University Health Network

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, University of Toronto

Study Record Dates

First Submitted

November 18, 2019

First Posted

March 6, 2020

Study Start

July 9, 2020

Primary Completion

September 28, 2021

Study Completion

September 28, 2021

Last Updated

December 10, 2021

Record last verified: 2021-12

Data Sharing

IPD Sharing
Will not share

Locations