NCT04295369

Brief Summary

This study will examine the effects of a smartphone-based lifestyle medicine (LM) for improving psychological well-being in Chinese population. Since a range of lifestyle factors are involved in the pathogenesis and progression of common mental disorders (e.g., depression and anxiety), modifying different lifestyle factors simultaneously may be effective to improve our psychological well-being. Chinese dietary recommendations will be integrated into the app to increase the acceptability towards mental health intervention. Through this study, we aim to promote evidence-based patient care and to improve help-seeking and access to evidence-based interventions for improving psychological well-being.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 10, 2020

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

February 28, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 4, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

March 4, 2020

Status Verified

March 1, 2020

Enrollment Period

3 months

First QC Date

February 28, 2020

Last Update Submit

March 3, 2020

Conditions

Keywords

Psychological Well-beingLifestyle MedicineSelf-helpDepressionAnxiety

Outcome Measures

Primary Outcomes (1)

  • Change in the Depression Anxiety Stress Scales-21

    DASS-21 is a 21-items scale, comprises of three sub-scales which measures the negative emotional states of depression, anxiety, and stress, over the past week. The DASS is based on a dimensional rather than a categorical conception of psychological disorder, thus it has no direct implications for the allocation of patients to discrete diagnostic categories. However, recommended cutoff scores for conventional severity labels (normal, moderate, severe) are given in the DASS Manual.

    Immediately post-treatment and 1-month post treatment

Secondary Outcomes (8)

  • Change in The Insomnia Severity Index (ISI)

    Baseline, immediately post-treatment and 1-month post treatment

  • Change in the Short Form (Six-Dimension) Health Survey (SF-6D)

    Baseline, immediately post-treatment and 1-month post treatment

  • Change in the Health-Promoting Lifestyle Profile (HPLP II)

    Baseline, immediately post-treatment and 1-month post treatment

  • Change in the Sheehan Disability Scale (SDS)

    Baseline, immediately post-treatment and 1-month post treatment

  • Change in the Credibility-Expectancy Questionnaire (CEQ)

    Baseline, immediately post-treatment and 1-month post treatment

  • +3 more secondary outcomes

Study Arms (2)

Lifestyle Medicine Group

EXPERIMENTAL
Behavioral: Lifestyle Medicine

Waitlist Control Group

NO INTERVENTION

Participants in the waitlist control group will receive the intervention after the immediate post-treatment assessment.

Interventions

Lifestyle intervention with components including physical activity, diet, relaxation/mindfulness, sleep, stress management, and Chinese dietary recommendations.

Lifestyle Medicine Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Hong Kong residents
  • Aged ≥ 18 years
  • Able to read Chinese and type in Chinese or English
  • Have an Internet-enabled mobile device (iOS or Android operating system)
  • Are willing to provide informed consent and comply with the trial protocol

You may not qualify if:

  • Have a Patient Health Questionnaire (PHQ-9) score ≥ 10
  • Have a Generalized Anxiety Disorder 7-Item Scale (GAD-7) ≥ 8
  • Current involvement in psychotherapy or unstable medication for depression and/or anxiety
  • Beck Depression Inventory (BDI-II) Item 9 score of at least 2 indicating a current moderate suicidal risk that requires active crisis management (referral information to professional services will be provided to those with serious suicidal risk)
  • Are having unsafe conditions and are not recommended for physical activity or a change in diet by physicians
  • Having major psychiatric, medical or neurocognitive disorders that make participation infeasible or interfere with the adherence to the lifestyle modification

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Chinese University of Hong Kong

Shatin, Hong Kong

RECRUITING

Related Publications (1)

  • Wong VW, Tong JT, Shi NK, Ng CH, Sarris J, Ho FY. Smartphone-delivered multicomponent lifestyle medicine intervention for improving mental health in a nonclinical population: a randomized controlled trial. Front Public Health. 2024 Jan 16;11:1231981. doi: 10.3389/fpubh.2023.1231981. eCollection 2023.

MeSH Terms

Conditions

Psychological Well-BeingDepressionAnxiety Disorders

Condition Hierarchy (Ancestors)

Personal SatisfactionBehaviorBehavioral SymptomsMental Disorders

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

February 28, 2020

First Posted

March 4, 2020

Study Start

February 10, 2020

Primary Completion

May 1, 2020

Study Completion

June 1, 2020

Last Updated

March 4, 2020

Record last verified: 2020-03

Locations