NCT04288882

Brief Summary

Overall Aim: This study is designed to assess the role of ballon-assisted enteroscopy in the management of obscure small intestinal disorders in a tertiary-care center in Upper Eygpt. Specific objectives:

  1. 1.Evaluate the technical success rate and causes of the procedure in our locality
  2. 2.Explore the value and safety of BAE in the diagnose and treatment of suspected small bowel diseases.
  3. 3.Assess patients' and endoscopists' satisfaction related to the procedure.
  4. 4.Define the indications, diagnostic yield and appropriatness of BAE in our center.
  5. 5.Determine the value of enteroscopy-obtained biopsy samples in the diagnosis.
  6. 6.Perform a cost analysis of BAE in relation to its diagnostic value/yield.
  7. 7.Report the therapeutic role of BAE in different small intestinal disorders.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2020

Typical duration for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 26, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 28, 2020

Completed
2 days until next milestone

Study Start

First participant enrolled

March 1, 2020

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2022

Completed
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2023

Completed
Last Updated

February 28, 2020

Status Verified

February 1, 2020

Enrollment Period

2 years

First QC Date

February 26, 2020

Last Update Submit

February 26, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Role of Balloon-Assisted Enteroscopy (BAE) in Diagnosis and Treatment of Small Intestinal Disorders

    This study is designed to assess the role of ballon-assisted enteroscopy in the management of obscure small intestinal disorders in a tertiary-care center in Upper Eygpt.

    baseline

Interventions

Role of Balloon-Assisted Enteroscopy (BAE) in management of Small Intestinal Disorders

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

After obtaining the appropriate consents, data pertaining to clinical history, physical examination and baseline laboratory investigations (complete blood count, kidney function, coagulation profile) for all cases of obscure small intestinal disorders. CT abdomen, conventional upper GI endoscopy and colonoscopy in addition to other modalities as the CT scan and angiography will be done for every patient as appropriate. All patients will be subjected to the BAE if these modalities are negative. BAE will be performed in an outpatient or inpatient setting under general anesthesia, although some patients may require only conscious sedation. Most procedures will be performed through the mouth (antegrade), although the (retrograde) approach, through the rectum, may be done resorted to allow better access to suspected lesions in the lower part of the small bowel.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Hashimoto R, Nakahori M, Matsuda T. Impact of Urgent Double-Balloon Enteroscopy on the Short-Term and Long-Term Outcomes in Overt Small Bowel Bleeding. Dig Dis Sci. 2019 Oct;64(10):2933-2938. doi: 10.1007/s10620-019-05627-1. Epub 2019 Apr 17.

    PMID: 30997580BACKGROUND

Central Study Contacts

Amira Mohammed, assistant

CONTACT

Nahed Makhlouf, professor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

February 26, 2020

First Posted

February 28, 2020

Study Start

March 1, 2020

Primary Completion

March 1, 2022

Study Completion

September 1, 2023

Last Updated

February 28, 2020

Record last verified: 2020-02