NCT04285385

Brief Summary

Dental anxiety is a common problem in dental care, the aim of this protocol is to evaluate the effect of lavender for the control of anxiety during a surgical dental extraction.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2020

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 21, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 26, 2020

Completed
4 days until next milestone

Study Start

First participant enrolled

March 1, 2020

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2020

Completed
Last Updated

February 26, 2020

Status Verified

February 1, 2020

Enrollment Period

Same day

First QC Date

February 21, 2020

Last Update Submit

February 24, 2020

Conditions

Keywords

aromatherapylavenderanxiety

Outcome Measures

Primary Outcomes (3)

  • Corah

    Corah's Dental Anxiety Scale (1-25). Non anxiety (0-8), moderate (9-12), high (13-14), severe (over 15)

    45 minutes before dental treatment

  • Cortisol

    Salivary Cortisol Testing (ng/mL)

    5 minutes Before aromatherapy

  • Cortisol

    Salivary Cortisol Testing (ng/mL)

    30 minutes after aromatherapy

Secondary Outcomes (6)

  • Heart rate

    5 minutes Before aromatherapy

  • Heart rate

    30 minutes after aromatherapy

  • Respiratory rate

    5 minutes Before aromatherapy

  • Respiratory rate

    30 minutes after aromatherapy

  • Arterial pressure

    5 minutes Before aromatherapy

  • +1 more secondary outcomes

Study Arms (2)

Aromatherapy

EXPERIMENTAL

0.10 ml of lavender essential oil 30 minutes prior surgery

Other: Lavender aromatherapy

Sham Aromatherapy

SHAM COMPARATOR

0.10 ml mineral oil 30 minutes prior surgery

Other: Sham aromatherapy

Interventions

0.10 ml of lavender essential oil

Aromatherapy

0.10 ml of mineral oil

Sham Aromatherapy

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Volunteer to take part in the study
  • Healthy patients
  • Patients signing the informed consent
  • Patients who need surgical removal of third molars

You may not qualify if:

  • Hypertensive patients
  • Patients with nasal congestion problems
  • Patients allergic to lavender.
  • Patients under treatment with anti depressants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Liliana Argueta-Figueroa, DMD PhD

    UABJO

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Rafael Torres, MD PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 21, 2020

First Posted

February 26, 2020

Study Start

March 1, 2020

Primary Completion

March 1, 2020

Study Completion

May 1, 2020

Last Updated

February 26, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will share

Measures of cortisol, vital sign, Corah scale, sex and age.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
Starting 6 months after publication in journal
Access Criteria
For meta analysis purposes, after contact with the PI