NCT04273971

Brief Summary

Preventive and rehabilitation programs include plyometric exercises to promote agility, power, and muscle activation pattern during jumping. These exercises also are known to cause a high mechanical load that increases the risk of a musculoskeletal injury. The knowledge regarding the musculoskeletal damage result from this configuration of exercise can help to elaborate safer and effective training and rehabilitation programs. In this study, the investigators will conduct a clinical trial to determine the acute effect of plyometric exercises on damage caused on different portions of quadriceps and biceps femoral's muscles and tendons of quadriceps, and biceps femoral, and its effects on mechanical properties.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Feb 2020

Longer than P75 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 13, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 18, 2020

Completed
2 days until next milestone

Study Start

First participant enrolled

February 20, 2020

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 5, 2021

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2022

Completed
Last Updated

November 5, 2020

Status Verified

November 1, 2020

Enrollment Period

1.6 years

First QC Date

February 13, 2020

Last Update Submit

November 4, 2020

Conditions

Keywords

AdultLower extermityPlyometric exerciseMuscle properties

Outcome Measures

Primary Outcomes (3)

  • Change from baseline of echo intensity of quadriceps and biceps femoral muscles

    Muscle echo intensity will be assessed for transversal and longitudinal ultrasonography images.

    Baseline, immediately after exercise and up to 48 hours exercise

  • Change from baseline stiffness of patellar tendon

    Patellar tendon stiffness during 5 seconds rampa contraction protocol. Patellar tendon stiffness will be estimate from force/deformation relationship of tendon.

    Baseline, immediately after exercise and up to 48 hours exercise

  • Change from baseline young modulus of patellar tendon

    Patellar tendon young modulus during rampa contraction protocol. Young modulus will be estimate from force/deformation relationship of tendon normalized to transverse section area of tendon.

    Baseline, immediately after exercise and up to 48 hours exercise

Secondary Outcomes (1)

  • Change from baseline echo intensity of quadriceps and biceps femoral tendons

    Baseline, immediately after exercise and up to 48 hours exercise

Other Outcomes (1)

  • Change from baseline muscle soreness of quadriceps and biceps femoral muscles

    Baseline and up to 48 hours exercise

Study Arms (1)

Plyometric exercise

EXPERIMENTAL
Other: Plyometric exercises

Interventions

Plyometric exercises will be composed of vertical jumps, box jumps, half squat jumps, high straight jumps, bounding jumps, drop jumps and 10-m sprint.

Plyometric exercise

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Who practice physical activity (except jump training);
  • No previous lower extremity muscle injury at least 6 months before the recruitment;
  • No previous lower extremity ligament or tendon injury or surgery;
  • No auditory, vestibular, visual or musculoskeletal injuries or disease that limit the execution of the exercise and assessment protocols;
  • No hypertension, cardiovascular, or respiratory disease.

You may not qualify if:

  • Body mass index greater than 30 kg/m².

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Karine Josibel Velasques Stoelben

Uruguaiana, Rio Grande do Sul, 97502772, Brazil

Location

MeSH Terms

Interventions

Plyometric Exercise

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Felipe P Carpes, PhD

    Universidade Federal do Pampa

    STUDY DIRECTOR
  • Marco A Vaz, PhD

    Federal University of Rio Grande do Sul

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
The statistical analyzer will be masking for the time factor.
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Single-arm design where all participants receive treatment.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 13, 2020

First Posted

February 18, 2020

Study Start

February 20, 2020

Primary Completion

October 5, 2021

Study Completion

March 30, 2022

Last Updated

November 5, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will share

The investigators intend to publish the results in an open-access journal, indexed at the Directory of Open Access Journals, with the copyrights transferred to the authors. Details regarding the study's design and statistical plan can be obtained consulting the trial's protocol. Data on other outcomes could be requested contacting the PI.

Shared Documents
STUDY PROTOCOL, SAP, CSR
Time Frame
The individual participant dataset will become available at a public repository up to six months after the first study publication
Access Criteria
A simple registration will grant access to study datasets. The website for these files is not defined at the time of registration.

Locations