An Investigation Into an Objective Measure of Muscle Quality, Function and Ability

NCT04269291 | Completed

• 1 other identifier: 7703
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The assessment of muscular function, quality and ability is of high importance in a diverse range of clinical disciplines from anaesthetics to physiotherapy. This study will look at the range of measurement techniques currently in use and development and considers their effectiveness and objectivity. It will also investigate whether an objective measurement technique can be found or developed that can be used both in the clinical environment and the community setting. This will focus on upper limb function and ability; ability is used here instead of strength since ability better describes functions needed for daily living rather than the maximum output a muscle is capable of.

Conditions

Electric Impedance; Healthy Volunteers

Keywords

electrical impedance; skeletal muscle

Outcome Measures

Primary Outcomes (1)

• Observation of healthy volunteer measurement of Electrical Impedance Myography in arm muscles.

  Primary Objective To measure EIM in sketetal arm muscle. Measurements to be made when the muscles are passive and when they are contracted. EIM measurements are reactance and resistance which are both measured in Ohms. At least 20 eligible and consented volunteers to be recruited and measured. To be measured at the one healthy volunteer visit. No other visits are part of the study.

  One visit per volunteer. Data to be accumulated over approximately 1 year

Secondary Outcomes (2)

• Age of participants

  through study completion, an average of 1 year

• Fitness health measure of participants

  through study completion, an average of 1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Healthy volunteers

You may qualify if:

• be volunteers
• be over the age of 18
• no pre-existing neuromuscular disease
• not have an implanted cardiac device
• be well at the time of measurement
• be able to give informed consent

You may not qualify if:

• Any existing neuromuscular disorder (eg multiple sclerosis, ALS, MND, CP)
• Any existing cardiac disease (including having a pacemaker or ICD)
• Active arthritis
• Be pregnant
• Any other implanted electrical device
• Not able to give informed consent

Sponsors & Collaborators

• Cardiff and Vale University Health Board: lead

Study Sites (1)

Cardiff and Vale University Health Board.

Cardiff, CF14 4XW, United Kingdom

Location

Study Officials

• Stephanie Wentworth

  stephanie.wentworth@wales.nhs.uk

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief Investigator

Study Record Dates

• First Submitted: January 15, 2020
• First Posted: February 13, 2020
• Study Start: June 18, 2020
• Primary Completion: September 1, 2021
• Study Completion: September 1, 2021
• Last Updated: March 14, 2022

Record last verified: 2022-03

Locations

GB (1)