NCT04266210

Brief Summary

The clinical performances of a restorative glass ionomer and a composite resin will be compared in the restoration of non-carious cervical lesions (NCCLs) at patients with systemic diseases. After recruiting participants with at least 2 NCCLs and at least one systemic disease, all restorations will be placed by a single clinician. All lesions will be cleaned before restoring. NCCLs will be divided into two groups: a conventional restorative glass ionomer cement \[Fuji Bulk (GC, Tokyo Japan) (FB)\] and a posterior composite resin \[G-ænial Posterior (GC, Tokyo Japan) (GP)\] All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using modified United States Public Health Service (USPHS) criteria after a week (baseline) 6, 12, 24, 36 and 48 months. Descriptive statistics will be performed using chi-square tests.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2018

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

February 10, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 12, 2020

Completed
3.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
Last Updated

March 10, 2025

Status Verified

March 1, 2025

Enrollment Period

2 months

First QC Date

February 10, 2020

Last Update Submit

March 7, 2025

Conditions

Keywords

non-caries cervical lesionsglass ionomercomposite resin

Outcome Measures

Primary Outcomes (1)

  • Clinical performances of different restoratiove systems

    Two year results according to USPHS criteria

    two years

Study Arms (2)

Fuji Bulk

EXPERIMENTAL

Glass ionomer (Fuji Bulk, GC, Tokyo Japan)

Device: Fuji Bulk

G-ænial Posterior

EXPERIMENTAL

Posterior composite resin(G-ænial Posterior, GC, Tokyo Japan)

Device: G-ænial Posterior

Interventions

Fuji BulkDEVICE

Restorative system

Fuji Bulk

Restorative system

G-ænial Posterior

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with at least one systemic disease such as hypertension, cancer in remission after chemotherapy or radiotherapy, diabetes mellitus, hemophilia, heart disease, coronary artery disease, rheumatoid arthritis, chronic obstructive pulmonary disease, lupus eritematozus.
  • Patients using medications for hypertension, diabetes mellitus, hemophilia, heart disease, coronary artery disease, rheumatoid arthritis, chronic obstructive pulmonary disease, lupus eritematozus.
  • Patients who are able to attend recall appointments.
  • Age greater than 18 years who had at least one systemic disease At least two NCCLs needed to be restored.
  • At least 20 teeth in occlusion.

You may not qualify if:

  • Non-vital teeth
  • Mobility of teeth
  • Severe periodontal disease
  • Heavy bruxism habit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Tooth Diseases

Condition Hierarchy (Ancestors)

Stomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

February 10, 2020

First Posted

February 12, 2020

Study Start

October 1, 2018

Primary Completion

December 1, 2018

Study Completion

December 1, 2023

Last Updated

March 10, 2025

Record last verified: 2025-03

Locations