NCT04263233

Brief Summary

This is an evaluation of a program developed by a team of nephrologists, operations experts and researchers. The goal is to provide CKD patients with a better way to transition to life on dialysis - one that emphasizes even more individual clinical, psychosocial and lifestyle needs. On top of high-quality clinical care, the 4-week Optimal Transition program supports patients as they adjust to treatment and learn to live the best life possible. This is done through a robust education curriculum and a trust-building approach.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2020

Typical duration for all trials

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 29, 2020

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

February 5, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 10, 2020

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 28, 2022

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

September 22, 2021

Status Verified

September 1, 2021

Enrollment Period

2.5 years

First QC Date

February 5, 2020

Last Update Submit

September 21, 2021

Conditions

Keywords

ESRDHemodialysisEducationEvaluation

Outcome Measures

Primary Outcomes (20)

  • Evaluation of clinical stabilization through standard clinical dialysis labs

    Evaluation of changes in the Standard of care monthly dialysis labs

    On admission, week 4 and day 90

  • Evaluation of clinical stabilization through standard clinical dialysis blood pressure measurements

    Evaluation of any changes in the Pre and post dialysis blood pressures for each patient which are collected as part of the patient's dialysis flow sheet.

    At week one and week 4.

  • Evaluation of clinical stabilization through standard clinical dialysis measurements of Intradialytic blood pressures

    Evaluation of any changes in the incidence of Intradialytic hypotension as assessed by review of the patient's dialysis flow sheet.

    At week one and week 4.

  • Evaluation of clinical stabilization through standard clinical dialysis measurements of ultrafiltration

    Evaluation of interval changes in the patient's ultrafiltration rates as measured by the dialysis machine and reported on the patient's dialysis flow sheets.

    At week one, week 4, day 90, day 180 and day 360.

  • Evaluation of clinical stabilization through standard clinical dialysis measurements of weight

    Target weight defined and achieved as measured by standard of care at the unit

    At week one and week 4, and changes between week one and week 4.

  • Evaluation of clinical stabilization through standard clinical dialysis measurements

    Dialysis access type as reported in the dialysis treatment sheets

    At week one and day 90

  • Evaluation of clinical stabilization through standard clinical dialysis collection of patient hospitalizations.

    Hospitalization rates as reported in the standard dialysis record for all patients

    Day 30, day 90, 6 months and 12 months

  • Evaluation of clinical stabilization through standard clinical dialysis records.

    Mortality rates as reported in the standard dialysis record for all patients

    Day 30, day 90, 6 months and 12 months

  • Evaluation of clinical and psychological stabilization through a quality of life measurement.

    The EQ-5D tool will be used

    Week 4

  • Evaluation of clinical and psychological stabilization through assessment of patient symptoms.

    The ESAS-r:Renal tool will be used

    Week 1 and Week 4

  • Satisfaction with the modality options education

    Survey of patient experience

    Week 1 and Week 4

  • Type of Dialysis Modality chosen by the patient

    Dialysis modality choice as reported by the patient

    Week 1 and Week 4

  • Actual Type of Dialysis Modality used by the patient

    Dialysis modality as reported on the standard dialysis treatment sheets

    week 4, month 3, 6, 12, 18 and 24

  • Evaluation of patient knowledge of dialysis and modalities

    Weekly focused one on one discussion where the patient is questioned about his/her understanding of dialysis, his/her progress, questions, concerns using a questionnaire developed by the investigator

    Week 1, 2, 3, 4

  • Evaluation of patient activation

    Survey measuring patient activation (PAM-13) survey

    Week 3 and month 3

  • Evaluation of patient satisfaction

    Survey of satisfaction with the program

    Week 4 or discharge from the program whichever comes first

  • Evaluation of the program process for time utilization

    Time per patient for visits from program start to completion for each patient

    Week 1 through week 4

  • Evaluation of the program process for cost utilization

    Time, and thus cost, for personnel to complete the program with each patient from entrance to completion or early termination.

    Week 1 through week 4

  • Evaluation of the feasibility of the program

    Number of referrals to the program and subsequent number of admissions to the program.

    Week 1 through week 4

  • Evaluation of the program efficiency

    Average length of stay for each patient in the program.

    Week 1 through week 4

Study Arms (1)

Other

This program, which is provided for all patients new to dialysis at the participating units, will be evaluated by assessing patient clinical outcomes and the results of surveys measuring patient-reported symptoms, quality of life, knowledge and activation. In addition, satisfaction with the program will be assessed.

Other: Analysis using descriptive statistics of patient clinical outcomes.Other: Surveys with participants using validated survey tools.Other: Evaluation of the program process including time, costs, referral rates, admission to the program and length of stay.

Interventions

Evaluation of the following: * Laboratory values at admission, week 4, and day 90. * Pre and post blood pressure at week one and week 4. * Intradialytic hypotension at week one and week 4. * Ultrafiltration rates at week one, week 4, day 90, day 180, and day 360. * Target weight defined and achievement in week one and week 4 and changes between week one and week 4. * Dialysis access type at week one and day 90. * Hospitalization and mortality rates.

Other

Surveys will assess participants' Symptom index, Quality of Life, Patient Activation as well as satisfaction with the program.

Other

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients referred by their treating nephrologist to one of the two Satellite Healthcare (SHC) participating centers who are new to dialysis and meet the inclusion/exclusion criteria.

You may qualify if:

  • Referred for incenter hemodialysis at one of two Satellite Healthcare (SHC) participating dialysis units
  • Without significant cognitive impairment;
  • Able to meaningfully interact with staff; and
  • Fluent in English (due to education material being limited to English at this time).

You may not qualify if:

  • Unable to meaningfully interact with staff;
  • Unable to read and understand English; or
  • Has significant cognitive impairment per the nephrologist or Principal Investigator

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Satellite Healthcare Oakland

Oakland, California, 94609, United States

RECRUITING

Satellite Healthcare Sacramento

Sacramento, California, 95834, United States

RECRUITING

Satellite Healthcare Chickasaw Gardens

Memphis, Tennessee, 38111, United States

RECRUITING

MeSH Terms

Conditions

Kidney Failure, Chronic

Interventions

Surveys and QuestionnairesCosts and Cost AnalysisLength of Stay

Condition Hierarchy (Ancestors)

Renal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthEconomicsHealth Care Economics and OrganizationsHospitalizationPatient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Wael F Hussein, MBBS

    Satellite Healthcare, Inc.

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 5, 2020

First Posted

February 10, 2020

Study Start

January 29, 2020

Primary Completion

July 28, 2022

Study Completion

December 31, 2022

Last Updated

September 22, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

Locations