Effects of Neuromuscular Training on Functional Capacity in Acute Coronary Syndrome Patients

NCT04246008 | Completed

• 1 other identifier: CEI18/111
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to analyse the effects of neuromuscular training on functional capacity in patients with acute coronary syndrome, compared to the classic strength training of the cardiac rehabilitation programs

Conditions

Acute Coronary Syndrome

Keywords

acute coronary syndrome; neuromuscular training; cardiac rehabilitation; functional capacity

Outcome Measures

Primary Outcomes (1)

• Incremental Shuttle Walking Test

  Maximum distance reached

  10 weeks

Secondary Outcomes (6)

• Chester Step Test

  10 weeks

• 30 seconds sit-to- stand test

  10 weeks

• Changes in hip muscle strength

  10 weeks

• Cardiopulmonary exercise testing

  10 weeks

• Sexual Health Inventory for Men

  10 weeks

Study Arms (2)

Neuromuscular training group

EXPERIMENTAL

This group will receive a 60-min neuromuscular training sessions twice a week, for 10 weeks until the completion of twenty sessions

Other: Neuromuscular training

Conventional training group

ACTIVE COMPARATOR

This group will receive a 60-min convencional cardiac rehabiliation session twice a week, for 10 weeks until the completion of twenty sessions

Other: Conventional strength training

Interventions

Neuromuscular training OTHER

The exercise training was developed based on assuring the correct performance of the exercise focusing in motor control.

Neuromuscular training group

Conventional strength training OTHER

The exercise training was developed based on standard strength training used in cardiac rehabiliation programmes

Conventional training group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Acute coronary syndrome patients
• Physical activity must have been prescribed

You may not qualify if:

• inflammatory cardiac disease
• severe or moderate ventricular dysfunction
• heart failure
• severe arrhytmias
• systemic hypertension \>95% percentile
• pulmonary hypertension \>40 mmHg
• aortic stenosis
• baseline O2 \<90%
• severe valve insufficiency

Sponsors & Collaborators

• Cardenal Herrera University: lead

Study Sites (1)

Arguisuelas Martinez Maria Dolores

Valencia, Spain

Location

Related Publications (4)

• EUROASPIRE I and II Group; European Action on Secondary Prevention by Intervention to Reduce Events. Clinical reality of coronary prevention guidelines: a comparison of EUROASPIRE I and II in nine countries. EUROASPIRE I and II Group. European Action on Secondary Prevention by Intervention to Reduce Events. Lancet. 2001 Mar 31;357(9261):995-1001. doi: 10.1016/s0140-6736(00)04235-5.

  PMID: 11293642 BACKGROUND

• Skou ST, Roos EM. Good Life with osteoArthritis in Denmark (GLA:D): evidence-based education and supervised neuromuscular exercise delivered by certified physiotherapists nationwide. BMC Musculoskelet Disord. 2017 Feb 7;18(1):72. doi: 10.1186/s12891-017-1439-y.

  PMID: 28173795 BACKGROUND

• Thompson PD, Arena R, Riebe D, Pescatello LS; American College of Sports Medicine. ACSM's new preparticipation health screening recommendations from ACSM's guidelines for exercise testing and prescription, ninth edition. Curr Sports Med Rep. 2013 Jul-Aug;12(4):215-7. doi: 10.1249/JSR.0b013e31829a68cf. No abstract available.

  PMID: 23851406 BACKGROUND

• Valtuena-Gimeno N, Fabregat-Andres O, Martinez-Hurtado I, Martinez-Olmos FJ, Lluesma-Vidal M, Arguisuelas MD, Ferrer-Sargues FJ. A cardiac rehabilitation programme based on neuromuscular training improves the functional capacity of patients with acute coronary syndrome: a preliminary randomised controlled trial. Physiotherapy. 2025 Mar;126:101428. doi: 10.1016/j.physio.2024.101428. Epub 2024 Sep 20.

  PMID: 39549308 DERIVED

MeSH Terms

Conditions

Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Study Officials

• Maria Dolores Arguisuelas

  Cardenal Herrera University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Physiotherapy Department

Model Details: This is a mixed-design study. It includes a two-group parallel, randomized clinical trial with acute coronary syndrome patients.

Study Record Dates

• First Submitted: January 27, 2020
• First Posted: January 29, 2020
• Study Start: February 1, 2021
• Primary Completion: July 30, 2021
• Study Completion: January 30, 2022
• Last Updated: March 10, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)