NCT04243031

Brief Summary

Approximately 225 samples, obtained from participants with varying risk factors for TB infection and disease, will be tested using the QFT Access Kit and the comparator device QFT-Plus.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 2020

Shorter than P25 for all trials

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 23, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 27, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

April 1, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2020

Completed
Last Updated

September 16, 2020

Status Verified

September 1, 2020

Enrollment Period

4 months

First QC Date

January 23, 2020

Last Update Submit

September 14, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • TB Result

    QFT Access result compared to the QFT-Plus result (positive, negative)

    At time of enrollment

Study Arms (1)

All subjects

Those with TB and those without TB.

Device: QFT Access

Interventions

Measure of Interferon Gamma

All subjects

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants coming to clinic

You may qualify if:

  • \. Be ≥ 18 years of age,
  • \. Have received no TB treatment or received treatment for less than 14 consecutive days.
  • \. Provide Informed Consent.

You may not qualify if:

  • \. Blood handling was not completed using QFT-Plus
  • \. Incubation was \<16 and \>24 hours
  • \. Improperly collected and/or stored samples per Instructions For Use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Biospecimen

Retention: SAMPLES WITH DNA

Plasma, whole blood

MeSH Terms

Conditions

Tuberculosis

Condition Hierarchy (Ancestors)

Mycobacterium InfectionsActinomycetales InfectionsGram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfections
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 23, 2020

First Posted

January 27, 2020

Study Start

April 1, 2020

Primary Completion

August 1, 2020

Study Completion

November 1, 2020

Last Updated

September 16, 2020

Record last verified: 2020-09

Data Sharing

IPD Sharing
Will not share