Trials Sponsors Conditions Drugs Pricing

Conditions

Diabetic Foot Infection Diabetic Foot Osteomyelitis Microbiome

Keywords

Diabetic Foot Osteomyelitis16S rRNAMetagenomesMicrobiome

Outcome Measures

Primary Outcomes (2)

Composition and Diversity of DFO with 16S rRNA Gene Data
Subjects who met the inclusion criteria for diabetic foot osteomyelitis (DFO) (sample size ≥ 10) and osteomyelitis without NDFO (sample size ≥ 10) were collected for debridement and amputation for 16s rDNA high-throughput sequencing. Compare microbe composition and diversity between the two groups.
2017-2018
Composition of the DFO Metagenome
Subjects who met the inclusion criteria for diabetic foot osteomyelitis (DFO) (sample size ≥ 10) and osteomyelitis without NDFO (sample size ≥ 10) were collected for debridement and amputation for Metagenomic Analysis. Compare microbe composition and diversity between the two groups.
2018-2019

Study Arms (2)

Dd group

Patients with diabetic foot osteomyelitis

ND group

Foot osteomyelitis without diabetes

Eligibility Criteria

Age18 Years - 80 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

patients with osteomyelitis

You may qualify if:

age≥18 years old.

Sponsors & Collaborators

Nanfang Hospital, Southern Medical University
Otherlead

Study Sites (1)

Department of Endocrinology and Metabolism, NanFang Hospital, Southern Medical University

Guangzhou, Guangdong, 510515, China

Related Publications (7)

Lavery LA, Peters EJ, Armstrong DG, Wendel CS, Murdoch DP, Lipsky BA. Risk factors for developing osteomyelitis in patients with diabetic foot wounds. Diabetes Res Clin Pract. 2009 Mar;83(3):347-52. doi: 10.1016/j.diabres.2008.11.030. Epub 2008 Dec 30.
PMID: 19117631BACKGROUND
Berendt AR, Peters EJ, Bakker K, Embil JM, Eneroth M, Hinchliffe RJ, Jeffcoate WJ, Lipsky BA, Senneville E, Teh J, Valk GD. Diabetic foot osteomyelitis: a progress report on diagnosis and a systematic review of treatment. Diabetes Metab Res Rev. 2008 May-Jun;24 Suppl 1:S145-61. doi: 10.1002/dmrr.836.
PMID: 18442163BACKGROUND

Study Officials

ying cao, doctor
Nanfang Hospital, Southern Medical University
PRINCIPAL INVESTIGATOR

Enrollment

28 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: associate professor

Study Record Dates

First Submitted

October 28, 2019

First Posted

January 27, 2020

Study Start

July 1, 2017

Actual (reported)

Studying on the Difference Between Two Kinds of Osteomyelitis

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Study Arms (2)

Dd group

ND group

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (7)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Study Arms (2)

Dd group

ND group

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (7)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations