Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
CRF-QoL
1 other identifier
observational
200
1 country
1
Brief Summary
To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2019
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 17, 2019
CompletedStudy Start
First participant enrolled
December 19, 2019
CompletedFirst Posted
Study publicly available on registry
January 22, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
May 31, 2025
CompletedApril 3, 2024
March 1, 2024
5.3 years
December 17, 2019
April 2, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
HRQoL score
Outcome of various HRQoL assessment tools.
Day 0: At the first outpatient clinical consultation with the clinical team
Secondary Outcomes (1)
Change in HRQoL score
6 months following first assessment for Outcome 1
Study Arms (2)
Non-invasive ventilation
Users of non-invasive ventilation
Long term tracheostomy ventilation
Long term tracheostomy ventilated patients
Interventions
Eligibility Criteria
Patients with chronic respiratory failure being treated with a form of ventilation of mechanical insufflation-exsufflation therapy.
You may qualify if:
- Diagnosed with chronic respiratory failure receiving any of:
- Non-invasive ventilation
- Prolonged mechanical ventilation
- Mechanical insufflation-exsufflation therapy
You may not qualify if:
- Aged \<18
- Significant physical or psychiatric co-morbidity that would prevent compliance with trial protocol
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Guy's and St. Thomas NHS Foundation Trust
London, SE1 7EH, United Kingdom
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Patrick Murphy, MBBS
Guy's and St Thomas' NHS Foundation Trust
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 17, 2019
First Posted
January 22, 2020
Study Start
December 19, 2019
Primary Completion
March 31, 2025
Study Completion
May 31, 2025
Last Updated
April 3, 2024
Record last verified: 2024-03
Data Sharing
- IPD Sharing
- Will not share