Perceptions of Illness Severity, Treatment Goals and Life Expectancy
ePISTLE
The ePISTLE Study: Perceptions of Illness Severity, Treatment Goals and Life Expectancy
1 other identifier
observational
120
1 country
1
Brief Summary
This study is exploring symptom burden, health experiences and expectations of treatment and survival of seriously ill dialysis patients and their physicians.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Nov 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 16, 2018
CompletedFirst Submitted
Initial submission to the registry
January 6, 2020
CompletedFirst Posted
Study publicly available on registry
January 13, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2024
CompletedOctober 20, 2022
October 1, 2022
6 years
January 6, 2020
October 19, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Current practice regarding discussion of prognosis with seriously ill dialysis patients, to better understand the dissonance between physician and patient beliefs on prognosis, transplant candidacy and goals of care.
Completion of questionnaire or structured interview
Through study completion, an average of 2 years
Secondary Outcomes (3)
Number of dialysis patients who are more optimistic about prognosis and transplant candidacy than their nephrologists
Through study completion, an average of 2 years
Patients' prognostic expectations are associated with their treatment preferences
Through study completion, an average of 2 years
Number of patients with dialysis associated symptoms as assessed by IPOS Renal (https://pos-pal.org/maix/ipos-renal-in-english.php).
7 days
Study Arms (2)
Hemodialysis patients
Patients undergoing hemodialysis
Peritoneal dialysis patients
Patients undergoing peritoneal dialysis
Interventions
No intervention
Eligibility Criteria
Dialysis patients
You may qualify if:
- Haemodialysis patients 18-100 years old, with a predicted mortality risk of \>20% in the next year, their close person and staff members (nurse and doctor) caring for the patient.
- Peritoneal dialysis patients 18-100 years old, with a predicted mortality risk of \>20% in the next year, their close person and staff members (nurse and doctor) caring for the patient.
You may not qualify if:
- Patients on home haemodialysis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Imperial College Healthcare NHS Trust
London, W12 0HS, United Kingdom
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Edwina Brown, MBChB
Imperial College London
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 6, 2020
First Posted
January 13, 2020
Study Start
November 16, 2018
Primary Completion
November 1, 2024
Study Completion
November 1, 2024
Last Updated
October 20, 2022
Record last verified: 2022-10