Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery
Clinical Performance of Two 0.2% Chlorhexidine Mouth Rinses After Periodontal Surgery. A Blinded, Intra-individual Cross-over Clinical Trial
1 other identifier
interventional
31
1 country
1
Brief Summary
Chlorhexidine is the gold standard of dental plaque prevention. Recent research have demonstrated that 0.2% Chlorhexidine solutions are more effective than 0.12% and 0.06% Chlorhexidine solutions. Several 0.2% solutions are available on the market. This study aimed to compare effectiveness of two commercially available 0.2% chlorhexidine mouthwashes. Patients, that after initial periodontal therapy, had a need for two periodontal surgeries, will be invited to join. After one surgical session, the patient will receive one 0.2% chlorhexidine solution, and after the next surgical session the patient will receive the other 0.2% chlorhexidine solution. Plaque and gingivitis will be recorded, as well as side effects.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_4
Started Mar 2019
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 20, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 20, 2019
CompletedFirst Submitted
Initial submission to the registry
January 7, 2020
CompletedFirst Posted
Study publicly available on registry
January 10, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2020
CompletedJanuary 13, 2020
January 1, 2020
9 months
January 7, 2020
January 8, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Plaque index
Dental Plaque
14 days intervention period
Gingival Index
Gingivitis
14 days intervention period
Study Arms (2)
Chlorhexidine 0.2% mouthwash control
EXPERIMENTALChlorhexidine 0.2%, Corsodyl Intervention rinsing 60 sec twice daily
Chlorhexidine 0.2% mouthwash with an Anti Discoloring System
EXPERIMENTALChlorhexidine 0.2%, Curasept Intervention rinsing 60 sec twice daily
Interventions
Comparison of Corsodyl and Curasept
Chlorhexidine 0.2% mouthwash with an Anti Discoloring System (ADS)
Eligibility Criteria
You may qualify if:
- Periodontitis, stage III and IV
You may not qualify if:
- Uncontrolled diabetes Systemic conditions associated with excessive bleeding Uncontrolled hypertension
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Erik Mauland
Oslo, 0574, Norway
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Anne Merete Aass, Professor
University of Oslo
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- DDS
Study Record Dates
First Submitted
January 7, 2020
First Posted
January 10, 2020
Study Start
March 20, 2019
Primary Completion
December 20, 2019
Study Completion
December 30, 2020
Last Updated
January 13, 2020
Record last verified: 2020-01
Data Sharing
- IPD Sharing
- Will share