NCT04220879

Brief Summary

In this retrospective observational study, we collected intraocular structure parameters of malignant glaucoma and primary angle closure glaucoma. Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography. To analyze the high risk factors and the possible pathogenesis of the disease and discuss the long-term effect of different treatment methods.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 25, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 5, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 7, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 24, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 24, 2020

Completed
Last Updated

January 7, 2020

Status Verified

January 1, 2020

Enrollment Period

9 months

First QC Date

January 5, 2020

Last Update Submit

January 5, 2020

Conditions

GlaucomaMalignant Glaucoma

Keywords

Malignant GlaucomaBiometric Measurements

Outcome Measures

Primary Outcomes (2)

  • Trabecular ciliary process angle

    TCPA is measured with its apex at the scleral spur, one arm along the posterior corneal surface, and another arm along the most anterior surface of the ciliary body

    baseline

  • Choroidal vascularity parameter

    Choroidal vascularity parameter is a vessel ratio measured by optical coherence tomographic images

    baseline

Study Arms (3)

Malignant Glaucoma

To determine the biometric measurements.

Fellow Eyes

To determine the biometric measurements.

Matched Eyes

To determine the biometric measurements.

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Outpatients \>=18 years old with or without malignant glaucoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhognshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, 510060, China

RECRUITING

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases

Study Officials

  • Chengguo O Zuo

    Zhognshan Ophthalmic Center, Sun Yat-sen University

    STUDY DIRECTOR

Central Study Contacts

Dingqiao O Wang, M.D

CONTACT

020-66615461wangdingqiao@163.com

Chengguo O Zuo, M.D,Ph.D

CONTACT

wangdingqiao@163.comchengguozuo@163.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 5, 2020

First Posted

January 7, 2020

Study Start

November 25, 2019

Primary Completion

August 24, 2020

Study Completion

November 24, 2020

Last Updated

January 7, 2020

Record last verified: 2020-01

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) needed to be keep security.

Locations

CN(1)