Analysis of the Glycemic Profile of People Suffering From Compulsive Eating Disorders Aiming to Offer an Innovative Nutritional Approach (GLUCOPULSE)

NCT04211818 | Completed

• 1 other identifier: RECHMPL18_0470
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Eating Disorders (ED) are a major public health problem. Current care remains only partially effective and the pathophysiology of the disorders remains to be deepened. With regard to compulsive ED (bulimia and binge eating disorder), our clinical experience suggests that one of the major triggers for crisis may be related to glycemia. In fact, bulimia could be considered as a vicious circle where the binge eating disorder is going to be followed by a food restriction in order to control weight , putting the subject in a situation of "energy deficiency" which will favor the emergence of new crises . Technological advances have resulted in the emergence of new measuring devices, such as "tracking", which records continuous glycemia, which would allow us to explore these clinical hypotheses.

Conditions

Bulimia; Binge Eating; Blood Glucose, Low; Crisis State; Compulsion

Outcome Measures

Primary Outcomes (1)

• Frequency of episodes of bulimia (measured from the dietary book) according to the interstitial glucose levels

  Each information entered on the dietary book will be positioned on a chronological axis allowing to identify precisely when the eating disorder occurred

  At the return of the dietary book (14 days after enrollment)

Secondary Outcomes (2)

• Levels of impulse to make a crisis and food obsession and hunger depending on interstitial glucose levels

  At the return of the dietary book (14 days after enrollment)

• Dietary patterns

  At enrollment

Study Arms (1)

Patients

EXPERIMENTAL

Behavioral: Eating Behavior; Biological: Blood glucose records

Interventions

Eating Behavior BEHAVIORAL

A dietary book will be given to the patient and will be filled by this one during 14 days

Patients

Blood glucose records BIOLOGICAL

A glycemic sensor will be placed at the back of the patient's arm

Patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Subject suffering from eating disorders with at least 3 episodes of bulimia per week for at least 2 months
• Subject affiliated to a health insurance or beneficiary of such a plan
• Subject able to understand the nature, purpose and methodology of the study
• Subject signed informed consent

You may not qualify if:

• Subject suffering from eating disorders such as anorexia nervosa
• Subject unable according to the investigator's opinion to keep updated a dietary book or to perform correctly the glycemic recordings
• Subject suffering from somatic pathology (ex: diabetes) or psychiatric pathology assessed by the MINI (ex : severe current major depressive episode) that may interfere with the protocol according to the the investigator
• Major subject legally protected (guardians or curators) or deprived of freedom by judicial or administrative order
• Pregnant or nursing woman

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

University Hospital

Montpellier, 34 295, France

Location

MeSH Terms

Conditions

Bulimia; Compulsive Behavior

Condition Hierarchy (Ancestors)

Hyperphagia; Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Impulsive Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 23, 2019
• First Posted: December 26, 2019
• Study Start: October 16, 2020
• Primary Completion: August 25, 2022
• Study Completion: July 1, 2023
• Last Updated: September 30, 2025

Record last verified: 2022-05

Locations

FR (1)