NCT04202120

Brief Summary

Memory performance is shown to be affected by age stereotypes among older adults. The purpose of the study is to examine the effects of age stereotype primes on episodic memory using priming intervention. The moderating effects of social participation is also examined.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 12, 2018

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

December 15, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 17, 2019

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

December 17, 2019

Status Verified

December 1, 2019

Enrollment Period

2.8 years

First QC Date

December 15, 2019

Last Update Submit

December 16, 2019

Conditions

Keywords

Age stereotypesepisodic memorysocial participation

Outcome Measures

Primary Outcomes (1)

  • Hong Kong List Learning Test

    The Hong Kong List Learning is a validated tool for assessing episodic memory for aged Chinese speaking adults (Chan, 2006). It was further taken for investigating differences among older adults with normal cognitive ability and older adults with mild cognitive impairment (Yeung et al., 2016). The random control list was taken in this study. It comprises 16 words formed by four categories:

    Change from baseline through study completion, an average of 2 hours

Study Arms (2)

Age-related priming

EXPERIMENTAL

Participants received a review of the profile of their social participation. They also received psycho-education about memory components. They were give given memory tests with age-related primes.

Other: Age-related stereotyping priming

Non-age related priming

ACTIVE COMPARATOR

Participants received a review of the profile of their social participation. They also received psycho-education about memory components. They were give given memory tests with NON age-related primes.

Other: Non age-related stereotype priming

Interventions

The priming intervention was performed using the E-prime 2.0 software (Psychology Software Tools, Pittsburgh, PA). To ensure the primes flashed on screen were beyond awareness, the similar adjustment procedure was taken (see Levy, 1996; Stein et al., 2002). After the trial block, participants were asked to try to report any words viewed during each trial. The stimulus onset asynchrony (SOA) will be reduced or enhanced whenever 2 words or above were correctly reported or no single word could be reported respectively. The priming SOA for this study ranged from 32 ms to 208 ms (M = 98.70 ms. SD = 48.60).

Age-related priming

he priming intervention was performed using the E-prime 2.0 software (Psychology Software Tools, Pittsburgh, PA). To ensure the primes flashed on screen were beyond awareness, the similar adjustment procedure was taken (see Levy, 1996; Stein et al., 2002). After the trial block, participants were asked to try to report any words viewed during each trial. The stimulus onset asynchrony (SOA) will be reduced or enhanced whenever 2 words or above were correctly reported or no single word could be reported respectively. The priming SOA for this study ranged from 32 ms to 208 ms (M = 98.70 ms. SD = 48.60).

Non-age related priming

Eligibility Criteria

Age55 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Indication of largely normal cognitive functioning as screened on the Montreal Cognitive Assessment (MoCA) with Hong Kong norms -

You may not qualify if:

  • Sensory deficits and evidence of cognitive impairment as screened on the Montreal Cognitive Assessment (MoCA) with Hong Kong norms

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Applied Social Sciences, Hong Kong Polytechnic University

Hong Kong, Hong Kong

RECRUITING

Related Publications (4)

  • Au A, Chan AS, Chiu H. Verbal learning in Alzheimer's dementia. J Int Neuropsychol Soc. 2003 Mar;9(3):363-75. doi: 10.1017/S1355617703930025.

    PMID: 12666761BACKGROUND
  • Wong A, Yiu S, Nasreddine Z, Leung KT, Lau A, Soo YOY, Wong LK, Mok V. Validity and reliability of two alternate versions of the Montreal Cognitive Assessment (Hong Kong version) for screening of Mild Neurocognitive Disorder. PLoS One. 2018 May 23;13(5):e0196344. doi: 10.1371/journal.pone.0196344. eCollection 2018.

    PMID: 29791452BACKGROUND
  • Stein R, Blanchard-Fields F, Hertzog C. The effects of age-stereotype priming on the memory performance of older adults. Exp Aging Res. 2002 Apr-Jun;28(2):169-81. doi: 10.1080/03610730252800184.

    PMID: 11928527BACKGROUND
  • Chan SCY, Au AML, Lai SMK. The detrimental impacts of negative age stereotypes on the episodic memory of older adults: does social participation moderate the effects? BMC Geriatr. 2020 Nov 5;20(1):452. doi: 10.1186/s12877-020-01833-z.

MeSH Terms

Conditions

Memory Disorders

Condition Hierarchy (Ancestors)

Neurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Alma Au, PhD

    Dr (female)

    STUDY CHAIR

Central Study Contacts

Stephen Chan, Masters

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 15, 2019

First Posted

December 17, 2019

Study Start

January 12, 2018

Primary Completion

October 31, 2020

Study Completion

December 31, 2020

Last Updated

December 17, 2019

Record last verified: 2019-12

Data Sharing

IPD Sharing
Will not share

Locations