NCT04201041

Brief Summary

Superficial dyspareunia represents a major health problem especially for the newly wed couples. Pulsed radiofrequency for pudendal nerve is a non-neurolytic neuromodulatory method that is effective in relief of this type of pain. Objectives: to evaluate the efficacy of bilateral pudendal nerve fluoroscopic guided pulsed radiofrequency in treatment of intractable non-organic dyspareunia, and compare between trans-gluteal and transvaginal approaches regarding patient comfort and satisfaction.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2018

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

December 11, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 16, 2019

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 20, 2020

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 25, 2020

Completed
Last Updated

April 9, 2020

Status Verified

April 1, 2020

Enrollment Period

1.3 years

First QC Date

December 11, 2019

Last Update Submit

April 7, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • change in Numerical rating scale

    0 no pain and 10 maximum pain

    baseline reading -1 day reading-3 days postoperative reading

Study Arms (2)

trans-gluteal approach

ACTIVE COMPARATOR

received pudendal nerve pulsed radiofrequency through trans-gluteal approach

Procedure: pudendal nerve pulsed radiofrequency

trans-vaginal approach

ACTIVE COMPARATOR

received pudendal nerve pulsed radiofrequency through trans-vaginal approach

Procedure: pudendal nerve pulsed radiofrequency

Interventions

received pudendal nerve pulsed radiofrequency through trans-vaginal approach or trans-gluteal approach

trans-gluteal approachtrans-vaginal approach

Eligibility Criteria

Age16 Years - 46 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • women aged between 16 and 46 years and from a near vicinity to our facility to make her available for follow-up

You may not qualify if:

  • We had excluded women with any abnormality in the transvaginal US guided imagining, or those with any evidence of local gynecological abnormalities on examination. Meanwhile, we had excluded those women with infection at site of injection, coagulopathy or other bleeding diathesis, pre-existing neurologic deficit in the targeted region, those with history of chronic opioid use and women who refused to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt

Asyut, 0020, Egypt

Location

Study Officials

  • Alaa Elzohry, MD

    South Egypt Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Professor

Study Record Dates

First Submitted

December 11, 2019

First Posted

December 16, 2019

Study Start

December 1, 2018

Primary Completion

March 20, 2020

Study Completion

March 25, 2020

Last Updated

April 9, 2020

Record last verified: 2020-04

Data Sharing

IPD Sharing
Will not share

Locations