Jaw Muscle Function in Patients With Tension-type Headache

NCT04196127 | Unknown

• 1 other identifier: 091219
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Patients with tension-type headache (TTH) and migraine often experience musculoskeletal complaints, like neck pain and/or jaw pain. Earlier studies have revealed an association between different headache types and neck pain and discussed the possible role of the cervical muscles. Furthermore, patients with neck pain show a decrease in motor control of the jaw, without having any other signs of TMD. Similarly, studies in patients with TMD have only found an indication for poorer neck muscle function. Patients with TMD also show a decrease in bite force and force steadiness compared to healthy controls. It is however, unknown if bite force and force steadiness are similarly impaired in patients with headache and/or neck pain. The current study will take a closer look at the jaw muscle function of in patients with TTH, with and without neck pain.

Conditions

Headache Disorders; Tension-Type Headache

Keywords

Bite force; Temporomandibular disorder; Neck pain

Outcome Measures

Primary Outcomes (1)

• Maximum Bite Force

  Maximum bite force in Newton, best out of three tests

  baseline

Secondary Outcomes (4)

• Bite Force Steadiness

  baseline

• Neck muscle function

  baseline

• Total Tenderness Score

  baseline

• Total Tenderness Score

  Immediately after muscle function testing (outcomes 1-3)

Other Outcomes (3)

• Numeric Pain Rating Scale

  baseline

• Numeric Pain Rating Scale

  Immediately after muscle function testing (outcomes 1-3)

• Prevalence of temporomandibular disorders

  baseline

Study Arms (2)

TTH

Patients with tension-type headache. They may not experience migraine, but can experience neck pain and/or temporomandibular dysfunction.

Other: Bite force testing

Healthy controls

Participants without frequent headaches. They may experience neck pain and/or temporomandibular dysfunction.

Other: Bite force testing

Interventions

Bite force testing OTHER

Maximum bite force examination with a force intra-oral measuring device

Healthy controls; TTH

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients will be recruited from the Danish Headache Center. Additionally the patients and healthy controls will be included from a Danish web page for trials www.forsoegsperson.dk and from a research data base in Danish Headache Center during 2019-2020. When the participants respond through the webpage through either mail or telephone, they will receive written information through mail. They will be informed that they have the right to take a family member or close related, And that the oral information will be postponed till all can participate.

You may qualify if:

• Age between 18 and 55 years old.
• Diagnosed Frequent episodic TTH (1-14 headache days / month) or chronic TTH (≥15 headache days/ month) based on the ICHD-3.
• Maximum 3 days of migraine per month.
• Signed informed acceptance of participation.

You may not qualify if:

• medication overuse headache (ICHD-3)
• missing more than 1 molar,
• previous whiplash or head trauma,
• other major physical or neurological diseases,
• diagnosed depression, other mental illness
• unable to understand and speak Danish.
• Pregnant or lactating women.

Sponsors & Collaborators

• Danish Headache Center: lead
• UMC Utrecht: collaborator
• Academic Centre for Dentistry in Amsterdam: collaborator

Study Sites (1)

Danish Headache Center Rigshospitalet - Glostrup

Glostrup Municipality, 2600, Denmark

RECRUITING

Related Publications (13)

• Armijo-Olivo S, Warren S, Fuentes J, Magee DJ. Clinical relevance vs. statistical significance: Using neck outcomes in patients with temporomandibular disorders as an example. Man Ther. 2011 Dec;16(6):563-72. doi: 10.1016/j.math.2011.05.006. Epub 2011 Jun 12.

  PMID: 21658987 BACKGROUND

• Ashina S, Bendtsen L, Lyngberg AC, Lipton RB, Hajiyeva N, Jensen R. Prevalence of neck pain in migraine and tension-type headache: a population study. Cephalalgia. 2015 Mar;35(3):211-9. doi: 10.1177/0333102414535110. Epub 2014 May 22.

  PMID: 24853166 BACKGROUND

• Ballenberger N, von Piekartz H, Danzeisen M, Hall T. Patterns of cervical and masticatory impairment in subgroups of people with temporomandibular disorders-an explorative approach based on factor analysis. Cranio. 2018 Mar;36(2):74-84. doi: 10.1080/08869634.2017.1297904. Epub 2017 Mar 20.

  PMID: 28317439 BACKGROUND

• Bendtsen L, Fernandez-de-la-Penas C. The role of muscles in tension-type headache. Curr Pain Headache Rep. 2011 Dec;15(6):451-8. doi: 10.1007/s11916-011-0216-0.

  PMID: 21735049 BACKGROUND

• Fernandez-de-las-Penas C, Perez-de-Heredia M, Molero-Sanchez A, Miangolarra-Page JC. Performance of the craniocervical flexion test, forward head posture, and headache clinical parameters in patients with chronic tension-type headache: a pilot study. J Orthop Sports Phys Ther. 2007 Feb;37(2):33-9. doi: 10.2519/jospt.2007.2401.

  PMID: 17366957 BACKGROUND

• Florencio LL, de Oliveira AS, Carvalho GF, Tolentino Gde A, Dach F, Bigal ME, Fernandez-de-las-Penas C, Bevilaqua Grossi D. Cervical Muscle Strength and Muscle Coactivation During Isometric Contractions in Patients With Migraine: A Cross-Sectional Study. Headache. 2015 Nov-Dec;55(10):1312-22. doi: 10.1111/head.12644. Epub 2015 Sep 21.

  PMID: 26388193 BACKGROUND

• de Groot RJ, Wetzels JW, Merkx MAW, Rosenberg AJWP, de Haan AFJ, van der Bilt A, Abbink JH, Speksnijder CM. Masticatory function and related factors after oral oncological treatment: A 5-year prospective study. Head Neck. 2019 Jan;41(1):216-224. doi: 10.1002/hed.25445. Epub 2018 Dec 15.

  PMID: 30552819 BACKGROUND

• Madsen BK, Sogaard K, Andersen LL, Skotte JH, Jensen RH. Neck and shoulder muscle strength in patients with tension-type headache: A case-control study. Cephalalgia. 2016 Jan;36(1):29-36. doi: 10.1177/0333102415576726. Epub 2015 Apr 1.

  PMID: 25834271 BACKGROUND

• Madsen BK, Sogaard K, Andersen LL, Skotte J, Tornoe B, Jensen RH. Neck/shoulder function in tension-type headache patients and the effect of strength training. J Pain Res. 2018 Feb 23;11:445-454. doi: 10.2147/JPR.S146050. eCollection 2018.

  PMID: 29503581 BACKGROUND

• Testa M, Geri T, Gizzi L, Petzke F, Falla D. Alterations in Masticatory Muscle Activation in People with Persistent Neck Pain Despite the Absence of Orofacial Pain or Temporomandibular Disorders. J Oral Facial Pain Headache. 2015 Fall;29(4):340-8. doi: 10.11607/ofph.1432.

  PMID: 26485381 BACKGROUND

• Testa M, Geri T, Pitance L, Lentz P, Gizzi L, Erlenwein J, Petkze F, Falla D. Alterations in jaw clenching force control in people with myogenic temporomandibular disorders. J Electromyogr Kinesiol. 2018 Dec;43:111-117. doi: 10.1016/j.jelekin.2018.07.007. Epub 2018 Jul 26.

  PMID: 30269020 BACKGROUND

• van der Meer HA, Speksnijder CM, Engelbert RHH, Lobbezoo F, Nijhuis-van der Sanden MWG, Visscher CM. The Association Between Headaches and Temporomandibular Disorders is Confounded by Bruxism and Somatic Symptoms. Clin J Pain. 2017 Sep;33(9):835-843. doi: 10.1097/AJP.0000000000000470.

  PMID: 28002094 BACKGROUND

• von Piekartz H, Pudelko A, Danzeisen M, Hall T, Ballenberger N. Do subjects with acute/subacute temporomandibular disorder have associated cervical impairments: A cross-sectional study. Man Ther. 2016 Dec;26:208-215. doi: 10.1016/j.math.2016.09.001. Epub 2016 Sep 23.

  PMID: 27744136 BACKGROUND

MeSH Terms

Conditions

Headache Disorders; Tension-Type Headache; Temporomandibular Joint Disorders; Neck Pain

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Headache Disorders, Primary; Craniomandibular Disorders; Mandibular Diseases; Jaw Diseases; Musculoskeletal Diseases; Joint Diseases; Muscular Diseases; Stomatognathic Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Bjarne Kjeldgaard Madsen, PT, PhD

  Danish Headache Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Bjarne Kjeldgaard Madsen, PT, PhD

CONTACT

+45 38 63 22 24; bjarne.kjeldgaard.madsen@regionh.dk

Dianna Bartolin Christiansen

CONTACT

+45 38 63 22 24; dianna.bartolin.christiansen@regionh.dk

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist, PhD

Study Record Dates

• First Submitted: December 6, 2019
• First Posted: December 12, 2019
• Study Start: December 6, 2019
• Primary Completion: June 30, 2021
• Study Completion: June 30, 2021
• Last Updated: December 12, 2019

Record last verified: 2019-12

Locations

DK (1)